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Cancer of the bladder is the fourth most common malignancy among males and the tenth most common malignancy among females. Each year in the United States, over 50,000 people develop bladder cancer, of whom more than 12,000 ultimately will die of this disease.

Bladder cancer tends to occur most commonly in individuals over 60 years of age. Cigarette smoking and exposure to certain industrially used chemicals (derivatives of compounds called arylamines) are strongly associated with the development of bladder cancer. The vast majority (approximately 90%) of these cancers originate in the lining cells of the bladder, known as urothelium or transitional epithelium.

The Johns Hopkins Medical Institutions is a leader in the treatment and investigative study of bladder cancer. We have created this Web site to give patients and physicians access to the latest clinical and research developments related to this disease, as well as to the multidisciplinary team assembled here to fight bladder cancer.

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Creation of Bladder Cancer Tissue Microarrays

Through the use of high throughput genetic technologies, such as cDNA microarrays and serial analysis of gene expression (SAGE), numerous new markers of cancer have been identified. read more >

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