Brigitte M. Ronnett, M.D.

Co-Investigator, Core C


Contact Information


The Johns Hopkins Hospital
Weinberg Bldg, Room 2242
Baltimore, MD 21231
(410) 614-2971


NorthWestern University, Evanston, IL.

B.A. (Chemistry), 1979-1982

University of Chicago, Pritzker School of Medicine.

M.D., 1982-1986

Johns Hopkins University School of Medicine.

Resident in Pathology, 1986-1989.

Memorial Sloan-Kettering Cancer Center, New York, NY.

Fellow in Pathology, 1989-1990

Johns Hopkins University School of Medicine.

Senior Clinical Fellow in Surgical Pathology, 1990-1991

Johns Hopkins University School of Medicine.

Fellow in Gynecologic Pathology, 1991-1993


Professional Experience


Instructor, Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD


Assistant Professor, Department of Pathology, The Johns Hospital, Baltimore, MD


Assistant Professor, Department of Gynecology and Obstetrics, The Johns Hopkins Hospital, Baltimore, MD


Associate Professor, Departments of Pathology and Gynecology & Obstetrics, The Johns Hospital, Baltimore, MD

Selected Publications
Ronnett BM, Kurman RJ, Zahn CM, Shmookler BM, Jablonski KA, Kass ME, Sugarbaker PH. Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential. Hum Pathol 1995;26:509-524.

Ronnett BM, Zahn CM, Kurman RJ, Kass ME, Sugarbaker PH, Shmookler BM. Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis: a clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to "pseudomyxoma peritonei." Am J Surg Pathol 1995;19:1390-1408.

Sugarbaker PH, Ronnett BM, Archer A, Averbach AM, Bland R, Chang D, Dalton RR, Ettinghausen SE, Jaquet P, Jelinek J, Kurman RJ, Koslowe P, Shmookler B, Stephens AD, Steves MA, Stuart OA, White S, Zahn CM, Zoetmulder FAN. Pseudomyxoma peritonei syndrome. Advances in Surgery 1996;30:233-280.

Ronnett BM, Shmookler BM, Diener-West M, Sugarbaker PH, Kurman RJ. Immunohistochemical evidence supporting the appendiceal origin of pseudomyxoma peritonei in women. Int J Gynecol Pathol 1997;16:1-9.

Ronnett BM, Shmookler BM, Sugarbaker PH, Kurman RJ. Pseudomyxoma peritonei: new concepts in diagnosis, origin, nomenclature, and relationship to mucinous borderline (low malignant potential) tumors of the ovary. In: Rosen PP, Fechner RE, eds. Anatomic Pathology 1997, vol. 2. Chicago, IL:ASCP Press;1997:197-226.

Ronnett BM, Kurman RJ, Shmookler BM, Sugarbaker PH, Young RH. The morphologic spectrum of ovarian metastases of appendiceal adenocarcinomas: a clinicopathologic and immunohistochemical analysis of tumors often misinterpreted as primary ovarian tumors or metastatic carcinoma from other gastrointestinal sites. Am J Surg Pathol 1997;21:1144-1155.

Seidman JD, Ronnett BM, Kurman RJ. Why abandoning the borderline category of ovarian tumors is beneficial. Contemp Ob Gyn, Oct. 1997:66-84.

Lax SF, Pizer ES, Ronnett BM, Kurman RJ. Clear cell carcinoma of the endometrium is characterized by a distinctive profile of p53, Ki-67, estrogen (ER) and progesterone receptor (PR) expression. Hum Pathol 1998;29:551-558.

Lax SF, Pizer ES, Ronnett BM, Kurman RJ. Comparison of estrogen and progesterone receptor, Ki-67 and p53 immunoreactivity in uterine endometrioid carcinoma and endometrioid carcinoma with squamous, mucinous, secretory, and ciliated cell differentiation. Hum Pathol 1998;29:924-931.

Kendall B, Ronnett BM, Isacson C, Cho KR, Hedrick L, Diener-West M, Kurman RJ. Reproducibility of the diagnosis of endometrial hyperplasia, atypical endometrial hyperplasia and well-differentiated carcinoma. Am J Surg Pathol 1998;22:1012-1019.

Geng L, Connolly DC, Isacson C, Ronnett BM, Cho KR. Atypical immature metaplasia (AIM) of the cervix. Is it related to high-grade squamous intraepithelial lesion (HSIL)? Hum Pathol 1999;30:345-351.

Riopel MA, Ronnett BM, Kurman RJ. Diagnostic criteria and behavior of ovarian intestinal-type mucinous tumors: atypical proliferative (borderline) tumors and intraepithelial, microinvasive, invasive, and metastatic carcinomas. Am J Surg Pathol 1999;23:617-635.

Szych C, Staebler A, Connolly DC, Wu R, Cho KR, Ronnett BM. Molecular genetic evidence supporting the clonality and appendiceal origin of pseudomyxoma peritonei in women. Am J Pathol 1999;154:1849-1855.

Ronnett BM, Manos MM, Ransley JE, Fetterman BJ, Kinney WK, Hurley LB, Shieh-Ngai J, Kurman RJ, Sherman ME. Atypical glandular cells of undetermined significance (AGUS): cytopathologic features, histopathologic results and human papillomavirus DNA detection. Hum Pathol 1999;30:816-825.

Sugarbaker PH, Shmookler B, Ronnett BM, Chang D. Pseudomyxoma peritonei. Brit J Surg 1999;86:842.

Lax S, Kurman RJ , Pizer ES, Wu L, Ronnett BM. A binary architectural grading system for uterine endometrioid carcinoma has superior reproducibility compared to FIGO grading and identifies subsets of advanced-stage tumors with favorable and unfavorable prognosis. Am J Surg Pathol 2000;24:1201-1208.

Chew SH, Williams R, Kurman RJ, Perlman EJ, Ronnett BM. Morphology and DNA content analysis in the evaluation of first trimester placentas for partial hydatidiform mole (PHM). Hum Pathol 2000;31:914-924.

Ronnett BM, Yan H, Kurman RJ, Shmookler BM, Wu L, Sugarbaker PH. Pseudomyxoma peritonei associated with disseminated peritoneal adenomucinosis has a significantly more favorable prognosis than peritoneal mucinous carcinomatosis. Cancer 2001 (In Press).

Shih IM, Yan H, Speyrer D, Shmookler BM, Sugarbaker PH, Ronnett BM. Molecular genetic analysis of appendiceal mucinous adenomas in identical twins, including one with pseudomyxoma peritonei. Am J Surg Pathol (In Press). 25:1095-99, 2001.  









Project 1

Project 2

Project 3

Project 4

Project 5

Project 6


Core A

Core B

Core C


Developmental Research Program


Career Development Program


Other Key Personnel






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