Bloomberg School of Public Health
B Sc, University of Maryland, 1966
Microbiology and Immunology
615 North Wolfe Street, Suite E5132
Baltimore, MD 21205
In the laboratory headed by Dr. Keerti V. Shah, I have been studying
the epidemiology and disease potential of papillomaviruses and
polyomaviruses for the last several years. We were instrumental in
establishing the causal relationship and distribution of Human
Papilloma Viruses (HPVs) to cervical cancer of humans in many
studies both in the United States and abroad. Our current studies
continue this effort that has expanded into other human cancers,
specifically those of the head and neck region.
In the past, we studied the SV40 virus of Rhesus monkeys and the
closely related human polyomaviruses BKV and JCV. Recent reports
from some laboratories suggest that SV40 is currently in the human
population and is associated with human tumors. We are now
investigating this possibility, looking for the virus itself in
tumors and evidence of transmission in the population using
human papillomavirus, cervical cancer, SV40
Engels AE, Sarkar
C, Daniel RW, Gravitt PE, Verma K, Quezado M, Shah KV: Absence
of Simian Virus 40 in human brain tumors from Northern India. Int J
Cancer 101: 348-352, 2002.
SV40 Working Group (RW Daniel, member): A multicenter evaluation of
assays for detection of SV40 DNA and results in masked mesothelioma
specimens. Cancer Epidemiol Biomarkers Prev 10: 523-532, 2001.
Shah KV, Daniel
RW, Tennant MK, Shah N, McKee JT Jr, Gaydos CA, Gaydos JC, and
Rompalo A: Diagnosis of human papillomavirus infection by dry
vaginal swabs in military women. Sex Trans Infect 77: 260-264, 2001.
Ahdieh L, Klein
RS, Burk R, Cu-Uvin S, Schuman P, Duerr A, Safaeian M, Astemborski
J, Daniel R, Shah K: Prevalence, incidence and type-specific
persistence of human papillomavirus in HIV-infected and HIV-negative
women. J Infect Dis 184: 682-690, 2001.
Gaydos CA, Shah N, Tennant M, Crotchfelt KA, Madico G, Quinn TC,
Daniel R, Shah KV, Gaydos JC, McKee Jr KT: Evaluation of use of a
single intravaginal swab to detect multiple sexually transmitted
infections in active-duty military women. Clin Infect Dis
Gillison ML, Koch
WM, Capone RB, Spafford M, Westra WH, Wu L, Zahurak ML, Daniel RW,
Viglione M, Symer DE, Shah KV, Sidransky D: Evidence for a causal
association between human papillomavirus and a subset of head and
JNCI 92: 709-720, 2000.
Daniel RW, Ahdieh
L, Hayden D, Cu-Uvin S, Shah KV: Intra-laboratory reproducibility of
human papillomavirus identification in cervical specimens by a
polymerase chain reaction-based assay. J Clin Virol 19: 187-193,