Richard Daniel, B.Sc.


Co-Investigator, Project 1


Research Associate,

Bloomberg School of Public Health

Academic Degrees
B Sc, University of Maryland, 1966

Departmental Affiliation

Molecular Microbiology and Immunology

Departmental Address
615 North Wolfe Street, Suite E5132
Baltimore, MD 21205

Phone: 410-955-6243
Fax: 410-955-0105




In the laboratory headed by Dr. Keerti V. Shah, I have been studying the epidemiology and disease potential of papillomaviruses and polyomaviruses for the last several years. We were instrumental in establishing the causal relationship and distribution of Human Papilloma Viruses (HPVs) to cervical cancer of humans in many studies both in the United States and abroad. Our current studies continue this effort that has expanded into other human cancers, specifically those of the head and neck region.

In the past, we studied the SV40 virus of Rhesus monkeys and the closely related human polyomaviruses BKV and JCV. Recent reports from some laboratories suggest that SV40 is currently in the human population and is associated with human tumors. We are now investigating this possibility, looking for the virus itself in tumors and evidence of transmission in the population using serological techniques.


human papillomavirus, cervical cancer, SV40

Selected Publications


Engels AE, Sarkar C, Daniel RW, Gravitt PE, Verma K, Quezado M, Shah KV: Absence
of Simian Virus 40 in human brain tumors from Northern India. Int J Cancer 101: 348-352, 2002.


The International SV40 Working Group (RW Daniel, member): A multicenter evaluation of assays for detection of SV40 DNA and results in masked mesothelioma specimens. Cancer Epidemiol Biomarkers Prev 10: 523-532, 2001.


Shah KV, Daniel RW, Tennant MK, Shah N, McKee JT Jr, Gaydos CA, Gaydos JC, and Rompalo A: Diagnosis of human papillomavirus infection by dry vaginal swabs in military women. Sex Trans Infect 77: 260-264, 2001.


Ahdieh L, Klein RS, Burk R, Cu-Uvin S, Schuman P, Duerr A, Safaeian M, Astemborski J, Daniel R, Shah K: Prevalence, incidence and type-specific persistence of human papillomavirus in HIV-infected and HIV-negative women. J Infect Dis 184: 682-690, 2001.


Rompalo AM, Gaydos CA, Shah N, Tennant M, Crotchfelt KA, Madico G, Quinn TC, Daniel R, Shah KV, Gaydos JC, McKee Jr KT: Evaluation of use of a single intravaginal swab to detect multiple sexually transmitted infections in active-duty military women. Clin Infect Dis 33:1455-1461, 2001.


Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, Zahurak ML, Daniel RW, Viglione M, Symer DE, Shah KV, Sidransky D: Evidence for a causal association between human papillomavirus and a subset of head and neck cancers.
JNCI 92: 709-720, 2000.


Daniel RW, Ahdieh L, Hayden D, Cu-Uvin S, Shah KV: Intra-laboratory reproducibility of human papillomavirus identification in cervical specimens by a polymerase chain reaction-based assay. J Clin Virol 19: 187-193, 2000.







Project 1




Keerti Shah

Patti Gravitt

Dorothy Rosenthal

Sudha Sivaram

Richard Daniel

Kathleen Cho




Joy Mays







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