Robert J. Kurman,
Investigator, Core C
Dr. Kurman is the Richard W. TeLinde
Distinguished Professor of Gynecologic Pathology at the Johns
Hopkins University School of Medicine with appointments in the
Departments of Gynecology and Obstetrics and Pathology and is the
Director of the Division of Gynecologic Pathology at the Johns
Hopkins Hospital. He is boarded in Pathology and Obstetrics and
Gynecology and has had a specific interest in gynecologic pathology
for nearly 30 years. Dr. Kurman is a national and internationally
recognized authority in the field of ovarian pathology and has
published extensively on all types of ovarian neoplasms (see
publications list below). His research has included work on germ
cell tumors, gonadal stromal tumors and in the last ten years
epithelial tumors with particular interest in borderline tumors. He
is the editor of Blausteinís Pathology of the Female Genital Tract
and in the 5th edition of the text which is currently in press he
co-authored the chapter on surface epithelial tumors of the ovary.
He is also on the WHO committee charged with revising the ovarian
tumor classification (work in progress). In addition, he receives
approximately 1,500 slide consultations a year on difficult
diagnostic problems, many involving ovarian pathology (particularly
borderline tumors and MPSCs), from throughout the US and abroad.
Queens College, New York, New York. B.A. (Chemistry), 1964
Upstate Medical Center, Syracuse, New York. M.D., 1968
Beth Israel Hospital, New York, New York. Intern in Medicine and
Peter Bent Brigham Hospital, Childrenís Hospital, Boston Hospital
for Women, Boston, Mass. Resident in Pathology, 7/1/69-6/30/71
Massachusetts General Hospital, Boston, Mass. Fellow in Gynecologic
Boston Hospital for Women, Boston, Mass. Resident in Obstetrics and
Armed Forces Institute of Pathology, Washington, D.C. Assistant
Chief, Division of Gynecologic and Breast Pathology, 7/1/73-6/30/76
Los Angeles County Hospital, University of Southern California, Los
Angeles, California. Resident in Obstetrics and Gynecology,
Associate Professor, Pathology and Obstetrics and
Gynecology, Georgetown University School of Medicine,
Professor, Pathology and Obstetrics and Gynecology,
Georgetown University School of Medicine, Washington, D.C.
Richard W. TeLinde Distinguished Professor of Gynecologic
Pathology, Gynecology and Obstetrics, and Pathology, Johns
Hopkins University School of Medicine, Baltimore, MD
Sherman ME, Bur ME, Kurman RJ: p53 in endometrial cancer and its
putative precursors: evidence for diverse pathways of tumorigenesis.
Hum Pathol 1995; 26:1268-1274.
Kurman RJ, Brady MF, Omura GA, Yordan E, Given FT, Kucera PR, Roman
LD: Preliminary analysis of the behavior of Stage I ovarian serous
tumors of low malignant potential: A Gynecologic Oncology Group
Study. J Clin Oncol 1995;13(11):2752-2756.
Burks RT, Sherman
ME, Kurman RJ. Micropapillary serous carcinoma of the ovary. A
distinctive low-grade carcinoma related to serous borderline tumors.
Am J Surg Pathol 1996; 20:1319-1330.
Seidman JD, Kurman RJ. Subclassification of serous borderline tumors
of the ovary into benign and malignant types. A clinicopathologic
study of 65 advanced stage cases. Am J Surg Pathol 1996;
Tashiro H, Isacson C, Levine R, Kurman RJ, Cho KR, Hedrick L. p53
gene mutations are common in uterine serous carcinoma and occur
early in their pathogenesis. Am J Pathol 1997;150:177-185.
Katabuchi H, Tashiro H, Cho KR, Kurman RJ, Ellenson LH.
Micropapillary serous carcinoma of the ovary: an immunohistochemical
and mutational analysis of p53. Int J Gynecol Pathol 1998;
17:54-60.Sherman ME, Lee JS, Burks RT, Struewing JP, Kurman RJ,
Hartge P. Histopathologic features of ovaries at increased risk for
carcinoma: A case-control analysis. Int J Gynecol Pathol 1999; 18:
Shih I-M, Kurman
RJ. Immunohistochemical localization of inhibin-I
in the placenta and gestational trophoblastic lesions. Int J Gynecol
Pathol 1999; 18(2): 144-150.
Riopel MA, Ronnett BM, Kurman RJ. Evaluation of diagnostic criteria
and behavior of ovarian intestinal-type mucinous tumors: Atypical
proliferative (borderline) tumors and intraepithelial, microinvasive,
and metastatic carcinomas. Am J Surg Pathol 1999; 23: 617-635.
H, Wang T-L, Chen C-H, Pai SI, Hung C-F, Lin K-Y, Kurman RJ, Pardoll
DM, Wu T-C.Targeting human papillomavirus type 16 E7 to the
endosomal/lysosomal vaccines against Murine human papillomavirus
type 16 E7-expressing tumors. Human Gene Therapy 1999; 10:
Lacey JV Jr.,
Brinton LA, Barnes WA, Gravitt PE, Greenberg MD, Hadjimichael OC,
McGowan L, Mortel R, Schwartz PE, Kurman RJ, Hildesheim A. Use of
hormone replacement therapy and adenocarcinomas and squamous cell
carcinomas of the uterine cervix. Gynecol Oncol 2000; 77: 149-154.
Wheeler DT, Bell
KA, Kurman RJ, Sherman ME. Minimal uterine serous carcinoma:
Diagnosis and clinicopathologic correlation. Am J Surg Pathol 2000;
24 (6): 797-806.
Hinton EL, Bobo
LD, Wu T-C, Kurman RJ, Viscidi RP. Detection of Chlamydia
Trachomatis Deoxyribonucleic Acid in archival paraffinized specimens
from chronic salpingitis cases using the polymerase chain reaction.
Fert Steril 2000; 74: 1-6.
Bell KA, Kurman,
RJ. A clinicopathologic analysis of atypical proliferative
(Borderline) tumors and well-differentiated endometrioid
adenocarcinoma of the ovary. Am J Surg Pathol 2000; 24 (11):
Kurman RJ. Endometrial hyperplasia. In Textbook of Gynecology, 2nd
Edition, LJ Copeland (ed.), WB Saunders Co., Philadelphia, PA, 2000,
Kurman RJ. Ovarian serous borderline tumors: A critical review of
the literature with emphasis on prognostic indicators. Hum Pathol
2000; 31: 539-557.
Seidman JD, Kurman RJ. Update on low malignant potential ovarian
tumors. Oncology 2000;14 (6): 910-911.
Stehman FB, Perez CA, Kurman RJ, Thigpen JT. Uterine Cervix. In
Principles and Practice of Gynecologic Oncology, Third ed., WJ
Hoskins, CA Perez and RC Young (eds). Lippincott, Williams and
Wilkins, Philadelphia, 2000, p 841-918.
Bell KA, Smith
Sehdev AE, Kurman RJ. Refined diagnostic criteria for implants
associated with ovarian atypical proliferative serous tumors
(borderline) with micropapillary serous carcinomas. Am J Surg Pathol
2001; 25 (4): 419-432.
Ronnett BM, Sherman ME, Kurman RJ. Endometrium. In Pathology of
Incipient Neoplasia, 3rd ed, DE Henson and J
Albores-Saavedra (eds), Oxford University Press, N.Y., 2001, pp.
I-T, Zaloudek C, Kurman RJ. Functioning tumors and tumor-like
conditions of the ovary. In: Principles and Practice of
Endocrinology and Metabolism 3rd ed. Becker KL (ed),
Lippincott Williams and Wilkins, Philadelphia, 2001 p.1009-15.