Robert J. Kurman, M.D.
 

Principal Investigator, Core C

 

 

Dr. Kurman is the Richard W. TeLinde Distinguished Professor of Gynecologic Pathology at the Johns Hopkins University School of Medicine with appointments in the Departments of Gynecology and Obstetrics and Pathology and is the Director of the Division of Gynecologic Pathology at the Johns Hopkins Hospital. He is boarded in Pathology and Obstetrics and Gynecology and has had a specific interest in gynecologic pathology for nearly 30 years. Dr. Kurman is a national and internationally recognized authority in the field of ovarian pathology and has published extensively on all types of ovarian neoplasms (see publications list below). His research has included work on germ cell tumors, gonadal stromal tumors and in the last ten years epithelial tumors with particular interest in borderline tumors. He is the editor of Blausteinís Pathology of the Female Genital Tract and in the 5th edition of the text which is currently in press he co-authored the chapter on surface epithelial tumors of the ovary. He is also on the WHO committee charged with revising the ovarian tumor classification (work in progress). In addition, he receives approximately 1,500 slide consultations a year on difficult diagnostic problems, many involving ovarian pathology (particularly borderline tumors and MPSCs), from throughout the US and abroad.

Education/Training
Queens College, New York, New York. B.A. (Chemistry), 1964
Upstate Medical Center, Syracuse, New York. M.D., 1968
Beth Israel Hospital, New York, New York. Intern in Medicine and Pathology, 7/1/68-6/30/69
Peter Bent Brigham Hospital, Childrenís Hospital, Boston Hospital for Women, Boston, Mass. Resident in Pathology, 7/1/69-6/30/71
Massachusetts General Hospital, Boston, Mass. Fellow in Gynecologic Pathology, 7/1/71-6/30/72
Boston Hospital for Women, Boston, Mass. Resident in Obstetrics and Gynecology, 7/1/72-6/30/73
Armed Forces Institute of Pathology, Washington, D.C. Assistant Chief, Division of Gynecologic and Breast Pathology, 7/1/73-6/30/76
Los Angeles County Hospital, University of Southern California, Los Angeles, California. Resident in Obstetrics and Gynecology, 7/1/76-6/30/78

Professional Experience


9/1/78-6/30/83


Associate Professor, Pathology and Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, D.C.


7/1/83-12/30/88


Professor, Pathology and Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, D.C.


1/4/89-present


Richard W. TeLinde Distinguished Professor of Gynecologic Pathology, Gynecology and Obstetrics, and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD



Selected Publications
Sherman ME, Bur ME, Kurman RJ: p53 in endometrial cancer and its putative precursors: evidence for diverse pathways of tumorigenesis. Hum Pathol 1995; 26:1268-1274.

Barnhill DR, Kurman RJ, Brady MF, Omura GA, Yordan E, Given FT, Kucera PR, Roman LD: Preliminary analysis of the behavior of Stage I ovarian serous tumors of low malignant potential: A Gynecologic Oncology Group Study. J Clin Oncol 1995;13(11):2752-2756.

Burks RT, Sherman ME, Kurman RJ. Micropapillary serous carcinoma of the ovary. A distinctive low-grade carcinoma related to serous borderline tumors. Am J Surg Pathol 1996; 20:1319-1330.

Seidman JD, Kurman RJ. Subclassification of serous borderline tumors of the ovary into benign and malignant types. A clinicopathologic study of 65 advanced stage cases. Am J Surg Pathol 1996; 20:1331-1345.

Tashiro H, Isacson C, Levine R, Kurman RJ, Cho KR, Hedrick L. p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis. Am J Pathol 1997;150:177-185.

Katabuchi H, Tashiro H, Cho KR, Kurman RJ, Ellenson LH. Micropapillary serous carcinoma of the ovary: an immunohistochemical and mutational analysis of p53. Int J Gynecol Pathol 1998; 17:54-60.Sherman ME, Lee JS, Burks RT, Struewing JP, Kurman RJ, Hartge P. Histopathologic features of ovaries at increased risk for carcinoma: A case-control analysis. Int J Gynecol Pathol 1999; 18: 151-157

Shih I-M, Kurman RJ. Immunohistochemical localization of inhibin-I in the placenta and gestational trophoblastic lesions. Int J Gynecol Pathol 1999; 18(2): 144-150.

Riopel MA, Ronnett BM, Kurman RJ. Evaluation of diagnostic criteria and behavior of ovarian intestinal-type mucinous tumors: Atypical proliferative (borderline) tumors and intraepithelial, microinvasive, and metastatic carcinomas. Am J Surg Pathol 1999; 23: 617-635.

Ji H, Wang T-L, Chen C-H, Pai SI, Hung C-F, Lin K-Y, Kurman RJ, Pardoll DM, Wu T-C.Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal vaccines against Murine human papillomavirus type 16 E7-expressing tumors. Human Gene Therapy 1999; 10: 2727-2740.

Lacey JV Jr., Brinton LA, Barnes WA, Gravitt PE, Greenberg MD, Hadjimichael OC, McGowan L, Mortel R, Schwartz PE, Kurman RJ, Hildesheim A. Use of hormone replacement therapy and adenocarcinomas and squamous cell carcinomas of the uterine cervix. Gynecol Oncol 2000; 77: 149-154.

Wheeler DT, Bell KA, Kurman RJ, Sherman ME. Minimal uterine serous carcinoma: Diagnosis and clinicopathologic correlation. Am J Surg Pathol 2000; 24 (6): 797-806.

Hinton EL, Bobo LD, Wu T-C, Kurman RJ, Viscidi RP. Detection of Chlamydia Trachomatis Deoxyribonucleic Acid in archival paraffinized specimens from chronic salpingitis cases using the polymerase chain reaction. Fert Steril 2000; 74: 1-6.

Bell KA, Kurman, RJ. A clinicopathologic analysis of atypical proliferative (Borderline) tumors and well-differentiated endometrioid adenocarcinoma of the ovary. Am J Surg Pathol 2000; 24 (11): 1465-1479.

Ronnett BM, Kurman RJ. Endometrial hyperplasia. In Textbook of Gynecology, 2nd Edition, LJ Copeland (ed.), WB Saunders Co., Philadelphia, PA, 2000, pp. 1289-1297.

Seidman JD, Kurman RJ. Ovarian serous borderline tumors: A critical review of the literature with emphasis on prognostic indicators. Hum Pathol 2000; 31: 539-557.

Seidman JD, Kurman RJ. Update on low malignant potential ovarian tumors. Oncology 2000;14 (6): 910-911.

Stehman FB, Perez CA, Kurman RJ, Thigpen JT. Uterine Cervix. In Principles and Practice of Gynecologic Oncology, Third ed., WJ Hoskins, CA Perez and RC Young (eds). Lippincott, Williams and Wilkins, Philadelphia, 2000, p 841-918.

Bell KA, Smith Sehdev AE, Kurman RJ. Refined diagnostic criteria for implants associated with ovarian atypical proliferative serous tumors (borderline) with micropapillary serous carcinomas. Am J Surg Pathol 2001; 25 (4): 419-432.

Ronnett BM, Sherman ME, Kurman RJ. Endometrium. In Pathology of Incipient Neoplasia, 3rd ed, DE Henson and J Albores-Saavedra (eds), Oxford University Press, N.Y., 2001, pp. 401-418. 100.

Yeh I-T, Zaloudek C, Kurman RJ. Functioning tumors and tumor-like conditions of the ovary. In: Principles and Practice of Endocrinology and Metabolism 3rd ed. Becker KL (ed), Lippincott Williams and Wilkins, Philadelphia, 2001 p.1009-15.

 

 
 

 

 

 

INVESTIGATORS AND PERSONNEL,

 

LISTED BY PROJECT, CORE OR PROGRAM

 

Project 1

Project 2

Project 3

Project 4

Project 5

Project 6

 

Core A

Core B

Core C

 

Developmental Research Program

 

Career Development Program

 

Other Key Personnel

 

 

 

 

 

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