Department of Pathology NEWS 2015

Portraits Missing!

The portraits of Drs. Bennett, Heptinstall, Yardley and Boitnott had faded over time and intense exposure to fluorescent lights. Norm Barker and his team in Pathology Photography and Graphics have taken on the task of restoring these portraits. As you can see below, Drs. Bennett, Heptinstall, Yardley and Boitnott look better than ever! The restored prints are being framed and we look forward to having them back in the hall in front of administration.

Restored photo of Dr. Heptinstall Restored photo of Dr. Bennett Restored photo of Drs. Yardley and Boitnott


~December 2015

Congratulations, Dr. Montgomery!

Dr. Elizabeth Montgomery in the Division of Gastrointestinal/Liver Pathology was selected by The Pathologist as a one of the Most Influential Laboratory Medicine Professionals in the world in 2015! Dr. Montgomery was selected by The Pathologist to their "Power List 2015" for her work in gastrointestinal and soft tissue pathology. Congratulations, Liz!



~December 2015

Retirement of Marcela "Cellie" Southerland

Marcela 'Cellie' Southerland

After 45 years at Johns Hopkins, Marcela "Cellie" Southerland is retiring. A sendoff reception will occur in the Meyer Basement Meeting room B105 on Thursday, December 17 from 2-3PM for all who would like to stop by to say farewell. Everyone who has made a tissue microarray (TMA) over the past 15 years knows Cellie and her work well. Cellie has personally generated over 1,000 TMAs for a variety of researchers that have resulted in hundreds of publications and significant scientific advances. The quality of her work has made the Johns Hopkins Department of Pathology a leader in the field of TMAs.

It has been an honor to work at Johns Hopkins University, the most famous and prestigious medical school in the country. I have witnessed the growth and advancements in all fields and I am so very happy to have been able to contribute to these, especially in TMA's. Cellie

Her present plans for retirement are to continue to do volunteer work with her church and Saint Jude's. She sings in the choir and is crocheting healing blankets for the sick. Cellie also likes to travel and has been enjoying cruises with her many friends and family.

Cellie has been performing histology related services at Johns Hopkins since 1971. She initially worked in the pathology laboratory at the Wilmer Eye Institute under Dr. Green. She then became the laboratory supervisor of the pathology laboratory in the Department of Dermatology. She performed Mohs histology and brought immunohistochemistry to the lab. When the Dermatology pathology laboratory was closed, she joined the Reference Histology Lab. This was followed by a short employment in the pathology laboratory in the Department of Neurology performing neuromuscular biopsy processing. She joined the Tissue Microarray Core Facility (now the Oncology Tissue Services [OTS] core) in 2000. In addition to making TMAs, Cellie has also provided histology services through the OTS core. Cellie will be turning over the TMA production capabilities to Andre Robinson, who has quickly obtained mastery of the specialized technique.

Cellie is a very remarkable person. She is conscientious, reliable, honest, motivated and kind. Her histology skills are unsurpassed. She is always willing to do the hard projects and get them done right. I think everyone who has had the pleasure of working with Cellie will agree that she is great to work with. She will really be missed.Helen Fedor, OTS Core Laboratory Manager

Please join us in wishing Cellie a long and enjoyable retirement.

Marc Halushka MD, PhD
Director, OTS Core

~December 2015

Congratulations, Dr. Ali!

Dr. Michael Henry, President of the ASC giving the award to Dr. Ali at the recent 63rd Annual Scientific Meeting in Chicago.
Dr. Michael Henry, President of the ASC giving the award to Dr. Ali at the recent
63rd Annual Scientific Meeting in Chicago.


The Excellence in Education Award is presented by the American Society of Cytopathology (ASC) in recognition of meritorious service or accomplishment in the field of Cytopathology education.

Outstanding service or contributions at the national level; active involvement in primary education; and major program accomplishments are examples of accomplishments worthy of recognition.

~December 2015

Faculty Retreat 2015 Pictures

The annual retreat of Department of Pathology was held on September 26, 2015, at our Mount Washington campus. Over 80 faculty and administrators participated in plenary discussions and breakout sessions. The five breakout sessions (education, research, patient care, precision medicine, and quality and safety) were led by our five Deputy Directors (Drs. Borowitz, Burns, Carroll, Gocke, and Hooper). With a wonderful emphasis on "one department," the retreat provided a great opportunity to bring the Department together and to plan our future. Challenging questions from "How can we be more effective mentors?" to "How can we change pathology?" were asked, discussed, and many times answered. We thank Vanessa and Ellen for organizing a great day! Enjoy the pictures below.

~November 2015

Pathology Symposium this week!

Third Annual Pathology Symposium
The Third Annual Johns Hopkins Pathology Symposium is this week, November 2-4, 2015. Login to view your registered events here. To view Symposium information, program, and map, click here. Many thanks to Lorraine Blagg, Barbara Parsons, and the planning committee for their hard work in organizing this event.



~November 2015

Retirement celebration for Dr. Noel Rose


Dr. Noel Rose had a wonderful sendoff to the next chapter of his long and illustrious career on October 6 in the West Reading Room of the Welch Library. Under John Singer Sargent's portrait of the Four Doctors, faculty, staff and students from the Johns Hopkins Bloomberg School of Public Health's Molecular Microbiology and Immunology (MMI) program as well as from the Department of Pathology wished him well in his move to Boston where he will be teaching part time at Harvard University.

Dr. Rose made enormous contributions to the academic community at the Johns Hopkins University and beyond for over 65 years. His research career was launched in 1950 with the pioneering studies on autoimmunity thyroditis in which he developed the first model of autoimmune disease that helped to initiate the modern era of autoimmune research. This was just the beginning of his remarkable career which included not only his landmark contributions in autoimmunity but also his extraordinary dedication to teaching which served to inspire and motivate countless students and his visionary role in clinical laboratory immunology.

Dr. Rose received his MD in 1964 from SUNY at Buffalo. He became a Professor of Microbiology there and was the director of Immunology until 1973 when he took a position as Professor and Chair of the Department of Immunology and Microbiology at Wayne State University in Detroit. In 1982, he came to Johns Hopkins and as a Professor and Chair of the Department of Immunology and Infectious Diseases in the Johns Hopkins University School of Public Health, and in 1994, Pathology named him the Director of the Division of Immunology for the Johns Hopkins University School of Medicine.

We wish Noel well in the next phase of his remarkable career!

~October 2015

Congratulations, Dr. Carroll!

Karen Carroll, M.D.
Karen Carroll, M.D., of Johns Hopkins Microbiology on left, receiving award from
Angela Caliendo, M.D., Ph.D., on behalf of the IDSA


Please congratulate Dr. Karen Carroll. Karen was awarded the prestigious 2015 Edward H. Kass Award for Clinical Excellence from the Infectious Diseases Society of America (IDSA) for her contributions to rapid diagnostics of infectious diseases. The award is a named lecture in memory of Dr. Edward Kass who was one of the founders of the Society. In association with the award, Karen delivered the Edward H. Kass Lecture at the Society's meeting on October 10, 2015, in San Diego. Congratulations, Karen!

~October 2015

Special Lecture

The Johns Hopkins Pathology Grand Rounds presents:

The Joseph C. Eggleston, M.D. Visiting Professor Lecture
in Surgical Pathology
Speaker: Louis Dehner, M.D.
Professor, Pathology and Immunology
Professor, Pathology in Pediatrics
Washington University School of Medicine
Lecture Title: PleuropulmonaryBlastoma.
The pathology and biology
Date: Thursday, October 15, 2015
Time: 9:00 am
Place: ZayedTower 2117 (Arcade)


~October 2015

Dr. Charache Memorial Service

Patricia Charache, M.D., D(ABMM) Patricia Charache, M.D., D(ABMM), distinguished Professor Emeritus of Pathology, Medicine and Oncology, a world-renowned infectious diseases specialist and medical microbiologist who practiced at Johns Hopkins Medicine for more than 50 years, died peacefully on September 12, 2015.

Dr. Charache, the daughter of two physicians, was born in Maplewood, New Jersey on December 26, 1929. She graduated from high school in 1948 and attended Oberlin College in Oberlin, Ohio from 1948-1951. During her matriculation at Oberlin she met and married her husband of 64 years, Dr. Samuel Charache. The newlyweds moved to New York and Dr. Charache subsequently attended Hunter College where she earned a B.A. in 1952. In 1953, on the advice of her husband, Dr. Charache applied to and was accepted by the New York University School of Medicine and was awarded her M.D. in 1957. During medical school, she began her lifelong love of microbiology spurred by research in Dr. Colin MacCleod's microbiology research laboratory. She did her internship in internal medicine at the Baltimore City Hospital (now Bayview Medical Center) from 1957-1958. From 1958 to 1962, Dr Charache did several research and clinical fellowships at the University of Pennsylvania and ultimately at the Johns Hopkins University School of Medicine, Division of Allergy and Infectious Diseases. More research training followed under the mentorship of Dr. Charles A. Janeway in the Department of Pediatrics at the Harvard University School of Medicine, Children's Hospital in Boston, Massachusetts where she worked on the immunology of rheumatic fever.

Dr. Charache's long and distinguished career at Johns Hopkins Medicine began in 1964. Her initial appointment was as an instructor in the School of Medicine in the Division of Infectious Diseases. From 1966-1969 she was also the Assistant Chief of Medicine at Baltimore City Hospitals with an academic appointment at the University of Maryland School of Medicine. She persevered in a male-dominated work environment taking jobs that were perceived as beneath the male faculty. No obstacle was insurmountable and she was a catalyst for change. Her microbiology career paralleled her infectious diseases consultative practice and as both Departments grew, her responsibilities and contributions grew proportionately. When Dr. Charache first arrived, the Microbiology Laboratory was part of the Department of Medicine and she served as the Medical Director from 1967-1970. The division evolved and became part of the Department of Pathology, and she served as the Director of the Division of Microbiology and its various laboratories for 20 years (1973-1993). As a result of her abundant energy and wise direction, the laboratory grew and obtained national recognition. She improved patient care by upgrading the quality of microbiology and she instilled a level of professionalism among the staff that she supported so tirelessly. She added faculty members and organizational structure, expanded services such as virology and molecular diagnostics and was responsible for launching an active applied research program. Her early research interests involved the detection of genetic abnormalities using immunologic approaches, and later in her career her focus was on the development of new approaches to detect microbial pathogens, including AIDS and tuberculosis. Her innovations included the development of a novel 19-test, agar-based, computer-assisted method of bacterial identification and susceptibility testing, which revolutionized testing and was in use in the clinical laboratory for 30 years. During her academic career she published over 100 peer-reviewed manuscripts and more than a dozen books or book chapters. She was promoted as the 30th woman Professor in the School of Medicine in 1992.

In 1993, she stepped down as Microbiology Director and became Deputy Director of Clinical Affairs, Physician Advisor, and Director of Quality Improvement for the Department of Pathology (1993-1996). Other responsibilities included Director of the Park Medical Laboratories (1996-2003) and an 18-month tenure as the Director of the Department of Pathology, Zayed Military Hospital and associated hospitals, Abu Dhabi, UAE. She also held a joint appointment in the Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health for many years. Finally, from 1998 until her retirement, she was the program director of Quality Assessment and Outcomes Research Programs.

Her service to the Department of Pathology was merely one facet of her commitment on many levels to Johns Hopkins Hospital and to the School of Medicine. In terms of service and administration, Dr. Charache served on over two dozen committees including the Medical Board and Medical Care Evaluation Committee. It was often said that she would do work that no one else wanted to tackle in areas such as risk management and credentialing. She was chair of the Department's Credentialing Committee for 17 years. She worked tirelessly and courageously to advocate for professional development of all faculty, especially women. Her insightful dedication to mentorship launched the careers of many professionals. Some of her protégés became prestigious academicians and laboratory directors. An impressive 12 medical technologists in her laboratory obtained their PhDs and another 30 individuals earned their Master's degrees. Dr. Charache participated in formal teaching of medical students, graduate students, Pathology residents and Fellows in Infectious Diseases and Microbiology. In recent years, she was a member of five thesis committees for PhD candidates and she chaired two of these.

Ever the patient advocate, she did not hesitate to promote patient safety and quality in many of her roles. "Dr. Pat", as she was often called, had a tenacity that compelled her to revisit issues that concerned her until matters were resolved to her satisfaction. Such dedication to patient care and quality and her excellence as a Microbiologist were recognized by professional organizations outside of Hopkins. She served on advisory boards and scientific committees to the FDA, NIH, CDC, CLIAC, and the American Society for Microbiology. In 2003 she was honored by the CDC for leadership contributions to its initiatives including the Clinical Laboratory Improvement Act (CLIA) and CLIAC. In 2007, she was selected by the Joint Commission on Accreditation of Hospitals (JCAHO) to chair the newly developed Pathology Advisory Council. The level of her national activities includes service on two quality-associated committees that reported directly to the Secretary of Health and Human Services.

As an academician, Dr. Charache served on the editorial boards of several microbiology and pathology journals and as a reviewer for over a dozen other journals. She served as the President of the Maryland Branch of the American Society for Microbiology and on over a dozen committees for the national organization, most recently as Chair of the American Society for Microbiology Center for the History of Microbiology. For her outstanding service for advancing the field of microbiology and for her service to the American Society for Microbiology, Dr. Charache received one of the most prestigious awards to be bestowed upon a clinical microbiologist by the ASM, the bioMeriéux Sonnenwirth Award for Excellence in Clinical Microbiology.

Dr. Pat's commitment extended beyond institutional and national service to the practice of microbiology at an international level. In service to the National Academy of Sciences as a member of the Board on Science and Technology, Dr. Charache traveled the globe and provided microbiology consultative services and mentorship to budding microbiologists and physicians in over 21 countries. Often this work required upgrading laboratory facilities and education. Additionally the list of other consultative services to ministries of health, WHO, private and public hospitals, and nonprofit children's organizations brings the countries visited during her career to well over 30. Her most recent international activities involved efforts to curb tuberculosis through the Johns Hopkins SMILE initiative and an NIH tuberculosis project.

Dr. Patricia Charache is survived by her husband, Samuel Charache, M.D., Professor Emeritus of Pathology and Medicine of the Johns Hopkins University School of Medicine, their daughter Barbara Elizabeth Coleman, R.N., research nurse at the Bayview Medical Center, four grandchildren (Debra, David, Dean and Daniel), her sister Jane Pier, and her brother Robert Connamacher.

Click here to view the Memorial Service.

~September 2015

The Johns Hopkins Atlas of Pancreatic Pathology in Chinese!


Thanks to the hard work of Toby Cornish, Ling Li and Qing K Li, a Chinese version of our popular iPAD application "The Johns Hopkins Atlas of Pancreatic Pathology" is now available! Set the language in the iPAD settings to English, the app is in English. Set the iPAD language setting to Simplified Chinese and the app is in Chinese! Click here for the apple itunes download page.


~August 2015

Congratulations Jonathan Ling!

We are proud to announce the outstanding achievement of current Pathobiology graduate student, Jonathan Ling for his recently published article in Science, titled:
"TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD"
Science. 2015 Aug 7;349(6248):650-5.
doi: 10.1126/science.aab0983.
Article link: www.ncbi.nlm.nih.gov/pubmed/26250685

Jonathan Ling comes from Boston, MA. He received his BS in Biomedical Engineering from Johns Hopkins in 2010. After taking several neuroscience classes, he joined a lab at Johns Hopkins and began researching the role of TARDBP and c9orf72 in the pathophysiology of FTD/ALS. Jon has taken advantage of the synergy between basic science and translational medicine that the Pathobiology program provides to further supplement his research experience.

Watch Jonathan Ling & Dr. Philip Wong take the ALS Ice Bucket Challenge! (As seen on CBS & Fox News)

~August 2015

PATHOLOGY WEBSITE REQUESTS SUBMISSIONS

Would you like to request a new website? Update a current site? Meet with the Pathology web team? The Pathology Web Steering Committee has established a new policy for submitting web requests. Use the form here (also linked through the 'Website Requests' link in the Pathology footer) to submit requests.

~July 2015

Eight Johns Hopkins Pathologists included in Castle Connolly's Top Doctors in Newsweek Health: Top Cancer Doctors 2015 Issue!

Newsweek Health: Top Cancer Doctors 2015 publication has just hit the newsstands! We would like to recognize our very own pathologists selected by Castle Connolly this year. In alphabetical order, they are:

  • Pedram Argani
  • Peter Burger
  • Jonathan Epstein
  • Ralph Hruban
  • Robert Kurman
  • Elizabeth Montgomery
  • Brigitte Ronnett
  • William Westra

Castle Connolly is a health and wellness engagement platform www.castleconnolly.com that provides consumers with personalized information, programs and resources to improve their health. It currently enjoys a viewership of 40 million worldwide.

~July 2015

Congratulations Dr. Cheryl Koh!

Congratulations to former Pathobiology graduate student, Cheryl Koh, Ph.D. for her recently published article in Nature, titled:
"MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis"
Nature 2015 Jul 11;523(7558):96-100. Epub 2015 May 11.

These authors contributed equally to this work.
Cheryl M. Koh & Marco Bezzi

Article Link:
www.nature.com/nature/journal/v523/n7558/full/nature14351.html

Cheryl Mei-Yi Koh, Ph.D.
Agency for Science, Technology & Research
Institute of Molecular and Cell Biology (IMCB)
Singapore 138673, Singapore

I am currently studying the role of the protein arginine methyltransferases PRMT5 and PRMT7 in normal hematopoiesis and in Myc-induced lymphomas. My PhD research focused on the network of Myc-driven oncogenic processes in prostate carcinogenesis and was carried out in the lab of Angelo M De Marzo, MD, PhD, at the Johns Hopkins University School of Medicine, USA.


~July 2015

Congratulations Dr. Mary Fowler!

Mary Glenn Fowler, M.D., M.P.H.Congratulations Professor Mary Glenn Fowler for being awarded the 2015 Constance B. Wofsy Women's Health Investigator Award. This prestigious award was established by the Adult Clinical Trials Group (ACTG) Network to recognize an outstanding researcher who has been active clinically in the care of HIV-positive women, active in researching questions important to women in living with HIV, active in the research networks, and dedicated to successfully mentoring junior investigators.

Dr. Mary Fowler (MD, MPH) is a professor of Pathology at the Johns Hopkins University School of Medicine, with appointment in the Johns Hopkins Bloomberg School of Public Health in the Department of International Health. In addition, she is the Executive Director for Makerere University-Johns Hopkins University (MU-JHU) Research Collaboration in Kampala, Uganda. Dr. Fowler is a Pediatrician by training with over 25 years experience working in clinical trial research directed at prevention of mother to child transmission of HIV and pediatric HIV treatment. She is a world recognized researcher in PMTCT and worked at both NIH and US Center for Disease Control (CDC) supporting pediatric treatment trials and PMTCT international trials prior to joining the faculty at Johns Hopkins U. School of Medicine in 2005. From 2005-2014, Professor Fowler worked full time onsite at the MU-JHU in Kampala, Uganda. She has been the Principal Investigator for an NIH-funded HIV Clinical Trial Unit in Uganda for the past nine years.

Dr. Fowler is the Chair of a large multi-site protocol, called PROMISE (1077BF/FF) study supported by NIH and the International Maternal Pediatrics Adolescent AIDS Clinical Trials (IMPAACT) network. She is an active contributor to the scientific agenda of the Clinical Research Maternal and Pediatric and Therapeutic scientific agendas. Dr. Fowler also serves on several US and international committees including the USPHS Task Force Perinatal HIV Guidelines Working Group, and the Advisory Board of the Elizabeth Glaser Pediatric AIDS Foundation. Dr. Fowler has over 120 peer reviewed journal articles on which she is a first, senior or co-author based on her 25 years of work on HIV perinatal prevention and pediatric HIV treatment. Her most recent research focus has been on reducing the risk of HIV transmission during breastfeeding and improving maternal adherence to triple antiretroviral regimens, assessing emergence of resistance with maternal PMTCT regimens and long term squelae of exposure to ARVs among HIV exposed but uninfected children.

More information can be obtained about Dr. Fowler's research study, PROMISE:

~July 2015

Congratulations Allison Chen!

High school student Allison Chen was awarded fourth place in the National History Day competition for her video on the life of William Henry Welch.



~July 2015

Dr. Risa B. Mann

Risa B. Mann, Professor Emeritus of Pathology and Oncology at Johns Hopkins University School of Medicine, died at her home in Chevy Chase, Maryland, surrounded by her family, on June 26th, 2015.

The funeral was held at Ohr Kodesh Congregation at 11:30am on Sunday, June 28th, 2015.

Shiva services for Risa Mann was on June 29th and June 30th at 7:30 pm.

Dr. Mann was born in Washington, D.C., to Fannye Fox Berman and Bernard Abraham Berman, DDS. She graduated from the Woodrow Wilson High School in 1964 and attended Vassar College as a Matthew Vassar Scholar. After two years at Vassar, where she was a member of the Daisy Chain, she pursued a combined B.A./M.D. degree from Johns Hopkins University; she graduated with honors, and was third in her medical school class of ninety-five students. She was elected to Phi Beta Kappa and the Alpha Omega Alpha Honor Medical Society.

After college, Dr. Mann was an intern, resident and chief resident in the Department of Pathology at Johns Hopkins. Aside from two years as a Senior Staff Fellow at the National Institutes of Health in the Hematopathology Section of the National Cancer Institute, Dr. Mann remained at Johns Hopkins for her entire career. She was promoted to full professor in 1995 and retired in 2004. Dr. Mann was the fortyfourth woman to serve as a full professor in the history of the Johns Hopkins University School of Medicine.

Dr. Mann's research focused on three areas: the characterization of the relationship of the Epstein-Barr virus and lympho proliferative disorders; the clinical pathological correlation of hematologic malignancies; and the classification of lymphomas for the National Cancer Institute, as a member of the National Pathology Panel for Lymphoma Clinical Studies.

Dr. Mann wrote numerous articles in peer-reviewed journals and contributed to major books on pathology. She lectured widely, both in the United States and abroad. She was a member of many professional societies, including the International Academy of Pathologists and the Society for Hematopathology. She also held several consultant appointments, including with the U.S. and Canadian Academy of Pathology and served on the Board of Editors of Modern Pathology and was a reviewer for numerous professional publications.

In addition, Dr. Mann taught pathology to second-year medical students, for which she won a Faculty Teaching Award. During her tenure, she introduced her students and colleagues to the story of Dr. Dorothy Reed Mendenhall (1874-1964), a fellow Hopkins Medical School graduate and a pioneering female pathologist who identified the Reed-Sternberg cell that characterizes Hodgkin's disease. Dr.Reed's work was the subject of Dr. Mann's Dean's Lecture, delivered at Johns Hopkins University School of Medicine on September 20th, 2002. In many ways, Dr. Mann continued the legacy of Dr. Reed Mendenhall, both in the areas of advancing women in medicine and in our understanding of Hodgkin's Lymphoma.

While at Johns Hopkins, Dr. Mann sat on several hospital committees, Professorial Promotions Committees and Search Committees for the chairs of several departments of Johns Hopkins Hospital, including the departments of Medicine and Ophthalmology.

In addition to her clinical practice, her research and her many administrative roles, Dr. Mann served as the head of the residency-training program for the Department of Pathology at Johns Hopkins for seventeen years. As the current chairman of the Department of Pathology, Dr. Ralph Hruban, stated, "Risa was the heart and soul of the Department of Pathology for more than two decades." In that role she worked to recruit the best and brightest doctors to the Johns Hopkins Department of Pathology. She also served a role model and mentor to countless younger doctors and medical students - as well known for her diagnostic abilities as she was for her sense of style, her warmth and her devotion to the residents and fellows she trained. In fact, she came to know her students professionally and personally and remained in contact with many of them until her death. She will be remembered not only as an excellent diagnostician but also as the best dressed and best looking doctor behind a microscope.

Dr. Mann was married for forty-eight years to Dr. John J. Mann, also on the faculty of the Johns Hopkins University School of Medicine, and is survived by him and by their two daughters, Gilda M. Zimmet (Brian Zimmet) and Stacie M. Kronthal (Eric Kronthal). The Drs. Mann not only enjoyed a long and happy marriage, but were also able to collaborate on many cases. Five grandchildren - Aaron, William, Flora, Jacob and Henry - also survive her. Dr. Mann has one sister, Judith Lipnick, who survives her, as well as several nieces and nephews.

~June 2015

Ralph Hruban, M.D., Named Baxley Professor of Pathology, Director, and Pathologist-in-Chief

Ralph H. Hruban, M.D.After a national search, Ralph H. Hruban, M.D., has been appointed Baxley Professor in Pathology and Director of the Pathology Department for the School of Medicine, and Director of Pathology for Johns Hopkins Medicine, and Pathologist-in-Chief for The Johns Hopkins Hospital effective July 1, 2015. Dr. Hruban has served as the Interim Director since February 2014. Dr. Paul Rothman and Ronald Peterson made the announcement on June 8, 2015. Congratulations and best wishes, Dr. Hruban! For more information, please see news release:


To the Johns Hopkins Medicine community

Dear Colleagues,

We are delighted to announce that Ralph Hruban has been named the Baxley Professor in Pathology, director of the pathology department for the school of medicine, director of pathology for Johns Hopkins Medicine and pathologist-in-chief for The Johns Hopkins Hospital. He will assume this new role on July 1, after serving as interim director and leading the department since February 2014.

Ralph is a highly respected senior member of the pathology faculty, director of the Sol Goldman Pancreatic Cancer Research Center and director of the Division of Gastrointestinal/Liver Pathology. A recognized innovator, he is a co-founder of the National Familial Pancreas Tumor Registry at Johns Hopkins and created an award-winning iPad application to teach pancreas pathology.

Renowned for his collaborative research, Ralph has been recognized by the Institute of Scientific Information as a highly cited researcher and by Essential Science Indicators as the most highly cited pancreatic cancer scientist. One of his numerous research contributions includes the characterization of PanINs, the precursor lesions that give rise to invasive pancreatic cancer. Published extensively in his field, Ralph has authored more than 600 peer-reviewed publications and five books, including a standard textbook on pancreatic pathology. He is a frequent speaker nationally and abroad.

Ralph has received numerous awards, including the Johns Hopkins University Distinguished Alumni Award, the Team Science Award from the American Association for Cancer Research and five teaching awards from the school of medicine. He was elected to the German National Academy of Sciences Leopoldina in 2013.

A member of the Johns Hopkins faculty for the last 25 years, Ralph earned his bachelor's degree from the University of Chicago and his medical degree from the Johns Hopkins School of Medicine. He completed his residency training in anatomic pathology at Johns Hopkins, serving as chief resident, and a fellowship in surgical pathology at Memorial Sloan-Kettering Cancer Center. He returned to Johns Hopkins in 1990 as an associate professor. He was promoted to professor in 1999.

We appreciate the diligence of the search committee, co-chaired by Antony Rosen and William Nelson.

Please join us in congratulating Ralph as he continues to advance the work of one of the largest departments in the school of medicine.

Sincerely,

Paul B. Rothman, M.D.
Dean of the Medical Faculty
CEO, Johns Hopkins Medicine

Ronald R. Peterson
President
The Johns Hopkins Hospital and Health System
EVP, Johns Hopkins Medicine

~June 2015

Dr. Jackson's Portrait Unveiling

After great anticipation, the Department of Pathology's official portrait of Dr. Jay Brooks Jackson, our former Director, was unveiled on Friday morning, June 5, 2015, in the Welch Library, following Pathology Grand Rounds. The portrait was unveiled in the Library's stately West Reading Room where the masterwork of John Singer Sargent, The Four Doctors, is on permanent display. Dr. Jackson's portrait was created by Lisa Egeli, a renowned third-generation artist, whose father Peter Egeli is known for his portraits of distinguished Hopkins faculty, including another former Director, Dr. Fred Sanfilippo. The portrait of Dr. Jackson is now hung in the Pathology Administration reception area in the Carnegie Building.

~June 2015

The Applied Physics Laboratory and the Johns Hopkins Pathology Department - The Beginning of New Research Partnerships

Learn more about new scientific collaborations underway with Pathology faculty --Drs. Tim Amukele, Aaron Tobian, Kathy Burns, and Matt Olsen -- and the Applied Physics Laboratory, the result of "speed-dating" matchups created by the Johns Hopkins University School of Medicine. For more information, please visit this link.

~June 2015

Congratulations to Dr. Syed Z. Ali!

Dr. Syed AliCongratulations to Dr. Syed Z. Ali! He is the recipient of this year's "Excellence in Education" Award from the American Society of Cytopathology. This is a very prestigious award and huge honor given for outstanding teaching. The Award will be presented to him at this year's 63rd Annual Scientific Meeting, November 13-16, 2015 in Chicago, IL.

 

 

 

 

~June 2015

Autoimmunity Day 2015

The 17th Annual Autoimmunity Day will be on June 5th, 2015 from 8:00 am to 4:00 pm at Bloomberg School of Public Health in Becton Dickinson - W1020. Click here to view the program.

~June 2015

Graduation Dinner on May 21, 2015

On Thursday, May 21st over 200 members of Department of Pathology family (faculty members, faculty assistants, residents, fellows, graduate students, and their guests) gathered together at the Waterfront Marriott for the annual Graduation Dinner to celebrate the year. The event began with a cocktail reception followed by a dinner program. The dinner program began with a welcome and research award recognition from Ralph Hruban, M.D., Interim Director of Pathology, and was capped with the Chief Residents (Liz Thompson, M.D., Ph.D. and Nathan Cuka, M.D.) and Chief Pathobiology student (Michael Urbanowski, B.S., M.S.) giving a 'Year in Review' for their respective programs. Below are some photos from the dinner.


(All photos taken by Frederick Dubs, Pathology Photography.)

~May 2015

JHU Business Plan Competition Winners

JHU Business Plan Competition Winners

A team consisting of individuals within the Department of Pathology, Johns Hopkins School of Medicine won the highly competitive Medical Technology Category (Graduate track) at this year's 16th annual Johns Hopkins University Business Plan Competition hosted by the Center for Leadership Education of JHU's Whiting School of Engineering.

The competition which was expanded last year to include applicants across the country began in February. 16 semi-finalists were selected in March before being further reduced to 8 finalists competing for the grand prize of $10,000 in the Medical Technology (Graduate Track) category. Team PathoVax emerged victorious defeating Hopkins-affiliated teams as well as external institutions such as Ohio State University, Tulane University and Yale University.

The Johns Hopkins Pathology-centric winning team- PathoVax - consisted of

  • Weijie Poh, a Ph.D. candidate at the Pathobiology PhD program (Faculty mentor: Dr James Herman)
  • Joshua Weiyuan Wang, a Post-doctoral fellow with the Department of Pathology, Division of Gynecologic Pathology (Faculty mentor: Dr Richard Roden)
  • Jessica Jeang, a research coordinator for the Specialized Program of Research Excellence (SPORE) in Cervical Cancer at the Johns Hopkins University School of Medicine, Department of Pathology, Division of Gynecologic Pathology (Faculty mentor: Dr TC Wu).
  • Nicholas Calcaterra, a PhD candidate at the Lieber Institute for Brain Development.

PathoVax's winning business plan revolved around RG-1 VLP, a second generation highly broad spectrum HPV vaccine co-developed by Dr Richard Roden, Professor of Pathology and Dr Reinhard Kirnbauer from Medical University Vienna. Dr Roden and Wang have also applied for a Maryland Innovation Initiative grant (MII), worth up to $100,000 to finalize translational studies on this broad spectrum vaccine and foster its journey from bench to bedside. A decision is expected in late May.

Wang commented said that the team benefitted from their diverse training in translational research, research planning and grant administration. The expert guidance of the faculty mentors in the department was also an important factor not only in training students and post-doctoral fellows to formulate meaningful research topics, but also to develop critical thinking skills beyond the bench.

For a complete list of the JHU Business Plan competition winners, click here.

~May 2015

Joseph C. Eggleston Award Winners

Congratulations to Marissa White and Dongmei Xing for their recent Eggleston Awards. The award is funded by the Eggleston family in memory of Dr. Joseph C. Eggleston, former Director of Surgical Pathology and Professor of Pathology. Dr. Marissa White is a PGY-II resident with interests in gynecologic pathology. The aim of Marissa's study is to evaluate the expression of steroidogenic factor 1 (SF-1) in a wide range of ovarian lesions and determine if SF-1 is a more sensitive and specific marker for sex cord-stromal tumors compared with traditional markers." Sex cord-stromal tumors of the ovary still represent an area of diagnostic difficulty in cases which lack classic morphology, and traditional sex cord-stromal immunohistochemical markers (inhibin/calretinin) do not resolve distinction from non-sex cord-stromal tumors in all cases. Dr. Dongmei Xing is a PGY-III resident who will be pursuing a gastrointestinal fellowship in 2016, focused her graduate research on the effect of HIF-1 on myofibroblast transformation in the cornea, and her post-graduate research on the effect of HIF-1 on wound healing of the skin.

~May 2015

Congratulations on winning the Biotech & Healthcare Case Competition!

The Hopkins Graduate Student Consulting Club (JHGCC) successfully hosted a Biotech & Healthcare Case Competition on Friday, Apr 10, 2015 at the Homewood campus. The Case Competition was a great success with more than 50 teams (over 200 people) registered and 8 judges representing various sponsoring consulting firms on the day. The event culminated in 5 finalist team presentations in front of the client team from Johns Hopkins Medicine International, who were pleased to see the variety and depth of the recommendations that the teams came up with. This event provided undergraduates, graduate students, and postdocs interested in a career in consulting a hands-on opportunity to solve a complex business case and network with professionals in the field.

The 1st place winner is a three-person team from the Pathology Department

Biotech and Healthcare Case Competition Winners
To learn more about the The Hopkins Graduate Student Consulting Club (JHGCC) and the competition, please click here.

~May 2015

Updated Department of Pathology Wall of Science

Department of Pathology Wall of Science


The Department of Pathology is proud of the academic interests of its faculty. Begun in 2005, our "Wall of Science" has continually displayed some of the most well-known and well-cited publications from our department's faculty. Each paper represents a peer-reviewed publication in which the first or last author was a primary member of Pathology. This past year the wall was expanded to contain 86 manuscripts that identify excellence across many areas of basic, translational, clinical and pathologic sciences.

"These papers are remarkable in the wide scope of their discoveries. They clearly indicate to visitors and to ourselves the magnitude of our contributions to research," said Marc Halushka, curator of the wall.

The Wall of Science can be viewed on the 4th floor of the Pathology building alongside the Pathology Library.

Wall of Science Quick Facts

  • Number of papers: 86
  • Number of faculty members with at least one manuscript: 35
  • Most manuscripts from one faculty member: 9 - Ralph Hruban
  • Most highly-cited manuscript: The genomic landscapes of human breast and colorectal cancers by Laura Wood et al (>2,000 Citations)
  • Oldest paper: Noel Rose - Studies on organ specificity. V. Changes in the thyroid glands of rabbits following active immunization with rabbit thyroid extracts. 1956

~May 2015

Congratulations Dr. Epstein!
Active surveillance for prostate cancer

Dr. Jonathan Epstein is featured on the cover of the April 2015 issue of the CAP Today. Dr. Epstein was a member of the panel that developed key consensus guidelines on the management of men with prostate cancer. The new guidelines highlight the importance of high-quality pathology and the opportunity for more men to be managed with active surveillance rather than surgery. In the article Dr. Epstein notes that he will soon be proposing a new five-level grading system for prostate cancer that more closely informs clinical needs.

~April 2015

Dr. Boitnott the Ball Player

Dr. B & Dr. M
There is a nice article on our Dr. John Boitnott in the Spring 2015 issue of Johns Hopkins Medicine. The article celebrates the friendship between John and Dr. Simeon Margolis ("Moan") which started when they were classmates in medical school here at Hopkins. Both John and Moan were drawn together, in part, by their love for (and talent in) basketball. Congratulations Dr. B!




~April 2015

Pathology Lab Tours

Celebrating National Lab Professionals Week:
Lab Week Tours - April 20-23, 2015. Click here for more info.

~April 2015

USCAP 2015

Our trainees were wonderfully well-represented at the 2015 meetings of the United States and Canadian Academy of Pathology in Boston, Massachusetts. Here are some photos from USCAP!

~March 2015

Pathology Grand Rounds - The Inaugural Fred and Janet Sanfilippo Visiting Professor Lecture


~March 2015

17th Annual Department of Pathology Young Investigators' Day, to be held on Monday, March 30th, from Noon - 4:00 p.m. in the Turner Concourse

This important event provides residents, fellows, and students with the opportunity to showcase their clinical, basic, or translational research efforts. This activity allows faculty, fellows, residents, and students to learn more about the diverse ongoing research in our department. Click here to visit the PYID site.

~March 2015

Microbiology Division Welcomes Patricia (Trish) J. Simner, Ph.D.

The Microbiology Division is pleased to welcome Dr. Patricia (Trish) J. Simner as Assistant Professor of Pathology and Director of the Bacteriology and Parasitology sections of the Microbiology Laboratory. Dr. Simner received her Ph.D. in medical microbiology and infectious diseases at the University of Manitoba, Winnipeg, Manitoba. Her thesis was on resistance mechanisms among gram-negative bacteria, specifically extended spectrum β-lactamases. In 2013, she completed a two-year postdoctoral fellowship in Medical Microbiology in the Department of Laboratory Medicine and Pathology at the Mayo School of Graduate Medical Education, Rochester MN, and she is certified by the American Board of Medical Microbiology. She comes to Hopkins after working 13 months as a Clinical Microbiologist at St. Boniface Hospital in Winnipeg, Manitoba and as an Assistant Professor at the University of Manitoba in the Department of Infectious Diseases and Medical Microbiology, Winnipeg, Manitoba. It is anticipated that Dr. Simner will continue her research focus in the area of Gram-negative bacterial resistance.

~March 2015

Wall Street Journal on Autopsies

The March 10, 2015 Wall Street Journal has an article on the value of the autopsy. Barbara Crain and Jody Hooper are quoted. Congratulations Barbara and Jody!

~March 2015

Congratulations Mario!

Mario Caturegli, MD, MPH, and colleagues published an extensive historical review of our residency training program (Archives of Pathology & Laboratory Medicine Vol. 139, No. 3, March 1, 2015. Abstract). Mario reviewed archival and departmental records from September 1899 to June 2014 and he created a database of pathology residents. He then analyzed resident in-service examinations, American Board of Pathology examinations, and career paths. Mario found that in 115 years the department trained 555 residents who came from 133 medical schools located in 23 countries. After training, 124 became professors of pathology, 31 chairs of pathology departments, 10 deans of medical schools, 5 were elected into the National Academy of Sciences, and 1 won the Nobel prize. We will be ordering reprints of this article. If you would like a reprint, simply contact Nancy Nath at nnath2@jhmi.edu.

~March 2015

More Speed Dating for Research

Twenty-two faculty members from the Department of Pathology held a "speed dating for research" event with 22 staff members from the Applied Physics Lab. The goal of the event was to foster research collaborations between the two groups. As you can see from the photos below, the event was simply a wonderful success. Both Pathology and the APL look forward to many years of fruitful collaborations!

~February 2015

New Neuroendocrine Tumor Web Page!

We have launched a new web page dedicated to neuroendocrine tumors (http://pathology.jhu.edu/neuroendocrine/index.php). This web page is not organ specific, but instead provides educational information for patients and their families on neuroendocrine tumors of all organs. These tumors include medullary carcinoma of the thyroid, carcinoid tumors of the lung, islet cell tumors of the pancreas, carcinoid tumors of the bowel, and even neuroendocrine tumors of the skin. We encourage you to visit the site and spread the word.

~February 2015

New Book on Cytopathology

Qing Kay Li, MD, PhD, is the co-editor of a wonderful new book "Diagnostic Cytopathology Board Review and Self-Assessment." This beautifully illustrated book contains a series of board-type questions with explanatory answers.

For more information on Kay Li's new book visit: www.springer.com/book/978-1-4939-1476-0
And to purchase her book visit: www.amazon.com/Diagnostic-Cytopathology-Board-Review/

Congratulations Kay Li!

~February 2015

Congratulations Mark!

Mark A. Marzinke, Ph.D. is a co-author on a paper that appeared in the Feb 5th issue of the New England Journal of Medicine. In this study of over 5,000 women in South Africa, Uganda, and Zimbabwe, the authors found that the drug regimens tested did not reduce the rates of HIV-1 transmission. The reason for this poorer than expected outcome was that compliance taking the study drugs was low. Mark helped lead the pharmacology work that was central to understanding the importance of patient adherence to their medication in preventing the transmission of HIV.

~February 2015

Traumatic Brain Injury

Dr. Vassilis Koliatsos and his team recently reported, in the journal Acta Neuropathologica Communications, their findings from detailed studies of autopsied brain tissue from five combat veterans. Koliatsos and colleagues found a distinct pattern of injury to nerve fibers in the frontal lobes of these patients, and hypothesize that these changes could impact memory, reasoning and decision-making. To learn more, visit:

www.cbsnews.com/news/hidden-brain-damage-seen-in-veterans-with-blast-injuries/

http://www.washingtonpost.com/national/health-science/wounds-of-war-that-never-heal

www.dailymail.co.uk/sciencetech/article-2913469/Shell-shock-solved-Scientists-pinpoint-brain-injury

~February 2015

Speed dating a success!

Over fifty faculty members from the Department of Pathology and from the Whiting School of Engineering participated in a "speed dating" event in which a group of faculty from the pathology department met with faculty from Whiting School to share their research. The "speed dating" forum was modeled after similar events held at the University of Wisconsin (http://education.wisc.edu/soe/news-events/news/2014/01/27/school-of-education-department-of-surgery-try-speed-dating-for-research). Each faculty member from the Whiting School spent 3-5 minutes with each faculty member from Pathology. The event helped bridge the divide between the two campuses (the School of Medicine and the Whiting School of Engineering), and helped foster cross campus collaborations. After the speed dating session, faculty enjoyed an informal wine and cheese hour at which faculty followed-up with other faculty on new collaborations.

~January 2015

Congratulations Norm Barker!

A nice review of Norm Barker's exhibit, "Hidden Beauty," at the Mutter Museum in Philadelphia appeared in the weekend edition (January 17-18) of the Wall Street Journal. The review, on page C12, features beautiful pictures from the exhibit. Congratulations Norm!

~January 2015

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