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Pathology Young Investigators’ Day
Poster Presentations

April 21, 2003

The 5th Annual Pathology Young Investigators' Day was held on Monday, April 21st in the Turner Concourse from 1:00 - 4:00 pm. Seventy-two posters were on display representing the work of residents, fellows and students in collaboration with Pathology Faculty. This annual event is a great opportunity to learn about the research being done in the Department of Pathology.

Congratulations to the award recipients!
The 27 Award-winning posters are highlighted yellow in the table below.

 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

1

Adegbola,
Onikepe

Student

Pathology

Pasternack

Basic

 

A pp32/SET Complex Regulates Tumor Cell Growth by Binding to pRB.

Adegbola/
Pasternack

In. Prep

   

2

Ansari-Lari,
Ali

 

Housestaff

GYN

Ronnett

Clinical

 

Distinction of Endocervical and Endometrial Adenocarcinomas: P16 Expression Correlated with Human Papillomavirus (HPV) DNA by In Situ Hybridization (ISH).

Ansari-Lari/
Ronnett

Ready for Submission

 

Amer Jnl of Surg Path

USCAP Annual Mtg

3

Ansari-Lari

 

Housestaff

Cyto

Ali

Clinical

Fine Needle Aspiration of Abdominal Fat Pad (FNAFP) for Amyloid Detection: A Clinically Useful Test?

Ansari-Lari/
Ali

In Submission

Diag Cytopath

Amer. Soc. of Cyto.
50th Annual Sci. Mtg.

4

Brody, Jonathan

 

Res.Fellow

Molecular Pathology

Pasternack

Basic

 

Control of Differentiation-Related Genes by pp32 (ANP32A).

Brody/
Pasternack

In Submission

American Journal of Pathology

Keystone Symposia: Chromatin: Organizing the Genome for Patterns of Gene Exp. in Hlth. and Disease

5

Brody,
Jonathon

 

Res.Fellow

Molecular Pathology

Pasternack

Basic

 

pp32 In Differentiation and Cancer.

Brody/
Pasternack

In Submission

American Journal of Pathology

Amer. Society for Investigative Pathology, FASEB

6

Broussard,
Jennifer

 

Housestaff

Pathology

Epstein

Clinical

 

Atypia in Inverted Papillomas: Pathology and Prognostic Significance.

Broussard,/
Epstein

In Prep

 

USCAP

7

Buetens
Orin

 

Clin. Fellow

Transfusion Medicine

Ness

Clinical

 

Evaluating the Presence of Anti-HLA Antibodies in Male Patients With and Without Red Blood Cell Alloantibodies.

Beutens, Ness

     
 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

8

Cao,
Denfeng

 

Housestaff

GI

Hruban & Iacobuzio-
Donahue
Basic

Differential Expression of Multiple Genes in Assoc. with DPC4/ SMAD4/ MADH4 Inactivation in Pancreatic Cancer.

Cao/
Iacobuzio-
Donahue

In Prep.   USCAP Annual Mtg

9

Curtis, Carmelle

 

Res. Fellow

GI

Goggins

Basic

 

Analysis of Fanconi Anemia Groups A, C, and G in National Familial Tumor Pancreatic Registry Samples.

Curtis /
Goggins

In Prep.

 

 

10

Dalai,
Sarat

Res. Fellow

Immuno

Sadegh-Nasseri

Basic

 

Antigen Presenting Cells in Induction of Anergy in Memory DC4+ Cells.

Dalai/
Sadegh-Nasseri

 

 

 

11

Fairweather, DeLisa

 

Res. Fellow

Immuno

Rose

Basic

 

IL-12Rbeta1 and TLR4 Signaling Increase IL-1beta and IL-18-Associated Myocarditis and Coxsackievirus Replication.

Fairweather/
Rose

In Press J. Immunol. 170, 2003

Regulatory & Effector Functions of Macrophages

12

Fan,
Xing

 

Res. Fellow

Neuro

Eberhart

Clinical

 

hTERT Gene Amplification and Increased mRNA Expression in CNS Embryonal Tumors.

Fan/
Eberhart

In Press

The Amerian Journal of Pathology

Amer. Assoc. for Cancer Research, 94th Annual

13

Farinola,
Maryam

 

Housestaff

Pathology

Epstein

Clinical

 

Cystic Renal Lesions (CRL): Cytopathologic Correlates and Differential Diagnoses on Fine Needle Aspiration (FNA).

Farinola/
Ali

To be Submitted

ACTA Cyto

Amer. Soc. of Cyto.
50th Annual Sci. Mtg.

 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

14

Farinola, Maryam

 

Housestaff

Path

Epstein

Clinical

 

Utility of Immunohistochemistry for Alpha-Methylacylcoa Racemase (AMACR) in Distinguishing Atrophic Prostate Cancer from Benign Atrophy.

Farinola/
Epstein

To be Submitted

Amer Jnl of Surg Path

USCAP Annual Mtg

15

Fukushima,
Noriyoshi

 

Res. Fellow

GI

Hruban & Goggins

Basic

 

Aberrant Methylation of Suppressor of Cytokine Signaling (SOCS-1) Gene in Pancreatic Ductal Neoplasms.

Fukushima/
Goggins

In Prep. British Journal of Cancer

USCAP Annual Mtg

16

Fukushima,
Noriyoshi

 

Res. Fellow

GI

Hruban & Goggins

Basic

Diagnosing Pancreatic Cancer Using Methylation Specific PCR Analysis of Pancreatic Juice.

Fukushima/
Goggins

Yes Cancer Biology & Therapy, 2:1, 159/1 - 159/6 The Lustgarten Foundation for Pancreatic Cancer Rsch

17

Halushka,
Marc

 

Housestaff

Pathology

Epstein

Clinical

 

The Addition of a Negative 34bE12 Stain to a Small Focus of Atypical Glands on Prostatic Core Biopsies Does Not Predict a Higher Incidence of Prostatic Adenocarcinoma on Follow Up Biopsies.

Halushka/ Epstein

Submitted   USCAP Annual Mtg

18

Hansel,
Donna

 

Clin. Fellow

GI

Maitra

Basic

 

Identification of Novel Cellular Targets in Biliary Tract Cancers Using Global Gene Expression Technology.

Hansel/
Maitra

In Prep.

 

USCAP Annual Mtg

19

Hansel,
Donna

 

Clin. Fellow

GI

Maitra

Basic

 

Increased Expression and Processing of the Alzheimer Amyloid Precursor Protein in Pancreatic Cancer May Influence Cellular Proliferation.

Hansel/
Maitra

In Prep.

 

AACR
 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

20

Hansel,
Donna

 

Clin. Fellow

GI

Maitra

Basic

 

Liver Metastases Arising from Pancreatic Endocrine Neoplasms Demonstrate Increased VEGF-C Expression.

Hansel/
Maitra

In Prep.

 

USCAP Annual Mtg

21

Hansel,
Donna

 

Clin. Fellow

GI

Maitra

Basic

 

Telomere Length Variation in Biliary Tract Metaplasia, Dysplasia, and Carcinoma.

Hansel/
Maitra

In Prep.

 

USCAP Annual Mtg

22

Hartman,
Isamu

 

Student

Immuno

Sadegh-Nasseri

Basic

 

Production of Recombinant TCR for Measurement of the Affinity and Kinetics of its Interaction with Short-Lived Peptide-MHC Complexes.

Hartman/
Sadegh-Nasseri

 

 

Immunology Gradmark Program, 1st Annual Retreat, Oct., 2002

23

Hosler,
Gregory

 

Housestaff

Cyto

Ali

Clinical

 

Inflammatory Pseudotumor (IPT) of the Lung and Liver: A Diagnostic Dilemma in Cytopathology.

Hosler/ Ali

in prep.

Int.J. Gyn
Pathol

American Society of Cytopathology

24

Iaconis,
Lori

 

Housestaff

Path

Ali

Clinical

 

Placental Site Nodule (PSN): A Previously Unrecognized Cause for Abnormal Cervico-Vaginal (CV) Smears.

Iaconis/Ali

    USCAP

25

Karhadkar,
Sunil

 

Res. Fellow

Urol Path

Berman

Basic

 

Hedgehog Pathway Activity Correlates with Prostate Cancer Progression and Promotes Tumor Growth.

Karhadkar/
Berman

In Prep

 

American Urological Association Annual Meeting, April, 2003
 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

26

Kim,
Tae Woo

 

Res. Fellow

GYN

Wu

Basic

 

Enhancement of Suicidal DNA Vaccine Potency by Delaying Suicidal DNA-Induced Apoptotic Cell Death.

Kim/
Wu

In Prep

Cancer Research  

27

Klevytska, Alexandra

 

Student

Neuro

Borchelt

Basic

 

Role of Nuclear Aggregates in the Pathogenesis of Huntington's Disease in Transgenic Mouse Models.

Klevytska/
Borchelt

 

 

Society for Neuroscience
Annual Mtg

28

Koopman, Jens

 

Res. Fellow

GI

Goggins
Ronnett,B.

Clinical

 

SELDI Approach for Biomarker Identification in Dx of Pancreatic Cancer.

Koopman /
Goggins

In Prep.

 

AACR

29

Kulezsa,
Peter

 

Housestaff

Path

Ali

Clinical

 

Hepatocellular Carcinoma (HCC): Is Cytologic Grading Possible on Fine Needle Aspiration (FNA)?

Kulezsa,
Ali

In Prep. ACTA Cyto Amer. Soc. of Cyto.
50th Annual Sci. Mtg.

30

Kumar,
Matam Vijay

 

Res. Fellow

Immuno

Detrick

Basic

 

Double Stranded RNA (poly I:C) Up Regulates Toll-Like Receptor 3 and Induces Interferon b in Human Retinal Pigment Epithelial Cells.

Kumar/
Detrick

In Prep. Investigavie Ophthalmology and Visual Science Jnl of Immuno

ARVO*

31

Laird,
Fiona

 

Res. Fellow

Neuro

Wong

Basic

 

The Deletion of BACE1 Rescues Cognitive Deficits in APPswe/PS1dE9 Mice.

Laird/
Wong

 

 

 

32

Matsubayashi,
Hiroyuki

 

Res. Fellow

GI

Goggins

Clinical

 

Menthylation of Cyclin D2 is Freq. Observed in Pan. Cancer but is also an Age-related Phenomenon in GI Tissues.

Matsubayashi/
Goggins

In Press  

 

 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

33

Meeker,
Alan

 

Res. Fellow

GU Path

DeMarzo

Basic

 

Direct Evidence of Telomere Length Abnormalities in a Wide Range of Epithelial Pre-Cancerous Lesions.

Meeker /
DeMarzo

Submitted

Cancer Research, 62: 6405-6409

USCAP & AACR

34

Mikolaenko,
Irina

 

Housestaff

Neuro

Troncoso

Clinical

 

Alpha-Synuclein Lesions in Autopsies from the Baltimore Longitudinal Study of Aging (BLSA).

Mikolaenko/
Troncoso

   

Neuropathology Meeting

35

Mirshahidi,
Saied

 

Res. Fellow

Immuno

Sadegh-Nasseri

Basic

 

Short-Lived Peptide-MHC Complexes Induce T Cell Anergy by Low Avidity Engagement of TCR.

Mirshahidi/
Sadegh-Nasseri

  Nature Immunology Oral Pres. at Antigen
Presentation Workshop III
Paris, Fr.

Ann'l Hopkins Immuno.
Prog. Retreat

36

Mohamood,
Abdiaziz

 

Res. Fello

Immuno

Hammad

Basic

 

Immunoregulartory Function of B220+ DN T Cells.

Hamad /
Schneck

In Prep.  

 

37

Nakayama,
Masashi

 

Res. Fellow

GU

DeMarzo

Basic

 

Quantitative Analysis of DNA Methyltransferase mRNA Isoforms in Human Prostate Cancer Reveals Overexpression of DNMT3a and DNMT3b.

Nakayama/ DeMarzo

In Prep.  

 

38

Nichols,
Lynette

 

Housestaff

GI

Iacobuzio-Donahue & Hruban

Clinical

 

Claudin 4 Is Overexpressed in Invasive Pancreatic Ductal Adenocarcinomas.

Nichols/
Iacobuzio-Donahue

Not Submitted Journal of Clinical Cancer

USCAP Annual Mtg

39

Parker,
Antony

 

Res. Fellow

Path

Eshleman, J

Basic

 

Phosphorylation Regulates Repair of Adenine:8-Oxoguanine (Al8-oxoG) Mispairs in Microsatellite Stable Colorectal Cancer Cell Lines.

Parker/
Eshleman, J.

In Prep.  

AACR

 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

40

Parker,
Antony

 

Res. Fellow

Path

Eshleman, J

Basic

 

Stable Antisense Human mutY in Microsatellite Stable Colorectal Cancer Cell Lines is Directly Assoc. Elevation of the Mutagenic Base 8-Oxoguanine.

Parker/
Eshleman, J.

In Prep.  

AACR

41

Parwani, Anil

 

Housestaff

Path

Ronnett

Clinical

 

Cervical Adenoid Basal Tumors Associated with Invasive Carcinoma: Clinicopathologic Features, Human Papillomavirus (HPV) DNA Detection, and p16 Over-Expression.

Parwani/
Ronnett

In Prep. Am. J. Surg. Path. USCAP, Mar. 2003

42

Parwani, Anil

 

Housestaff

Path

Ali

Clinical

 

Hepatic Core Biopsy (HCB) Accompanying Fine Needle Aspirations (FNA): A Clinically Redundant Diagnostic Procedure?

Parwani/
Ali

In Prep. ACTA Cyto ASC, Nov. 2002

43

Parwani, Anil

 

Housestaff

Path

Ali

Clinical

 

Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas: Cytopathologic Correlates and Diagnostic Pitfalls.

Parwani/
Ali

In Prep. Diag Cytopath ASC, Nov. 2002

44

Parwani, Anil

 

Housestaff

Path

Ronnett

Clinical

 

Prostate Carcinoma with Squamous Differentiation: An Analysis of 33 Cases.

Parwani/
Epstein

In Prep. Am. J. Surg. Path. USCAP, March 2003

45

Pu, Robert

 

Clin. Fellow

Cyto

Clark

Clinical

 

Methylation Profiles to Differentiate Benign and Malignant Breast Lesions in Surgical and Cytological Specimens.

Pu/
Clark

 

 

USCAP Annual Mtg.

46

Pu, Robert

 

Clin. Fellow

Cyto

Clark

Clinical

 

Multiplex-MSP as a Potential Ancillary Tool in Urothelial Surgical Pathology and Cytopathology.

Pu/
Clark

 

 

USCAP Annual Mtg

 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

47

Rahman,
Ayman

 

Student

GI

Maitra

Basic

 

Loss of p27 Nuclear Expression in a Prognostically Favorable Subset of Pancreatic Endocrine Neoplasms.

Rahman/
Hansel

In Prep.

 

USCAP Annual Mtg.

48

Rajaii,
Fatemeh (Pouneh)

 

Student

Mol. Path

Pasternack

Basic

 

Down-Regulation of pp32 Expression Alters the Differentiation Status and Morphology of Cancer Cell Lines from Different Origins.

Rajaii/
Pasternack

 

 

 

49

Sahin,
Fikret

 

Res. Fellow

GI

Su

Basic

 

Loss of Stk 11/Lkb1 Expression in Pancreatic and Biliary Neoplasms.

Sahin
/Su

 

Accepted by: Modern Pathology

 

50

Sato,
Norihiro

 

Res. Fellow

GI

Goggins

Basic

 

Discovery of Novel Targets for Aberrant Methylation in Pancreatic Carcinoma Using High-Throughput Microarrays.

Sato/
Goggins

In Submission Cancer Research  

51

Sato,
Norihiro

 

Res. Fellow

GI

Goggins

Basic

 

SPARC/Ostionectin is a Frequent Target for Aberrant Methylation in Pancreatic Adenocarcinoma and a Potential Mediator of Tumor-Stromal Interactions.

Sato/
Goggins

In Submission Oncogene AACR

52

Scorpio,
Diana

 

Res. Fellow

Comp. Path

Dumler

Basic

 

The Role of Reactive Nitrogen Species and Phagocyte Oxidase in Immunopathology Induced by Tick-borne Anaplasma Phagocytophilum in a Murine Model of Human Anaplasmosis.

Scorpio /
Dumler

     

53

Sharma, Rajni

 

Res. Fellow

Immuno

Burek

Basic

 

Iodine Enhances ICAM-1 Expression on Thyrocytes of NOD.H2h4 Mice.

Sharma/
Burek

In Prep.

 

Environmental Factors in Autoimmune Diseases, 3/4-3/5/03
 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last Authors

Published

Citation

Poster

54

Sharma,
Rajni

Res. Fellow

Immuno

Burek

Basic

Role of NKT Cell in the Pathogenesis of Autoimmune Thyroiditis.

Sharma/
Burek

In Prep.

 

 

55

Shi,
Chanjuan

 

Res. Fellow

GI

Eshleman, J.

Basic

 

Anti-Gene Padlocks of Various Lengths Selectively Kill Bacteria Cells with Chromosome Targets.

Shi/
Eshleman, J.

 

 

AACR 4/5 - 4/9/03

56

Silverman,
Benjamin

 

Student

Path

Clarke

Basic

 

Proteomic Characterization of Renal Transplant Rejection Using Surface Enhanced Laser Desorption/Ionization (SELDI) Mass Spectrometry.

Silverman/
Clarke

In Press

Annals of Surgery,
Vol. 237, No. 5,
May 2003

Amer. Assoc. of Clinical
Chemistry Annual Mtg.
August, 2002

57

Swierczynski,
Sharon

 

Housestaff

GI

Maitra

Clinical

 

Development and Validation of Tissue Microarrays in Pancreatic Cancer.

Swierczynski/
Maitra

In Prep.

 

USCAP Annual Mtg.

58

Swierczynski,
Sharon

 

Housestaff

GI

Argani

Clinical

 

Identification of Novel Tumor Markers in Biliary Carcinomas Using Tissue Microarrays.

Swierczynski/
Argani

In Prep.

 

USCAP Annual Mtg.

59

Swierczynski,
Sharon

 

Housestaff

Cyto

Ali

Clinical

 

Impact of Liquid-based Gynecologic Cytology on a Human Immunodeficiency Virus-positive Population.

Swierczynski/
Ali

In Prep.

 

USCAP Annual Mtg.
3/22-3/28/03

60

Wang,
Min

 

Res.Fellow

Neuro

Burger

Clinical

 

"Angiocentric Bipolar" Astrocytoma: A Distinctive Infiltrating Astrocytoma.

Wang /
Burger

 

 

78th Annual Mtg of Amer
Assoc of Neuropathologists,

 

Name

Appt

Division

Faculty Preceptor

Type

Poster Title

First & Last
Authors

Published

Citation

Poster

61

White, C. Nicole

 

Res. Fellow

Clin Chem

Chan, D.

 

Basic

 

Intra-Calibration of Mass Spectrometry

White/ Chan

 

 

 

62

Xu,
Guilian

 

 

Res.Fellow

Neuro

Borchelt

Basic

 

Quantitative Assessment of b-Amyloid, Tau and Other Aggregated Proteins in the Brains of AD Patients and Transgenic Mice.

Xu/
Borchelt

Yes

Alzheimer's Dis. & Assoc. Disorders, 2002, Jul-Sep, 16(3):196-201, 191-5

8th Intn'l Conf.
on Alzheimer's Disease
& Related Disorders

63

Yang, Bin

 

Clin. Fellow

Cyto

Clark & Rosenthal

Clinical

 

Aberrant Promoter Methylation of HIC-1 in Human Pleomorphic Sarcoma.

Yang/
Goldblum

In Prep

  USCAP Annual Mtg.

64

Yang, Bin

 

Clin. Fellow

Cyto

Clark & Rosenthal

Clinical

 

Aberrant Promoter Methylation Profile of Tumor Suppressor Genes in Hepatocellular Carcinoma.

Yang/
Clark

In Prep

  USCAP Annual Mtg

65

Yang, Bin

 

Clin. Fellow

Cyto

Clark & Rosenthal

Clinical

 

Detection of Promoter Methylation of Multiple Tumor Suppressor Genes in Surgical and Cytologic Specimens of Cholangiocarcinoma.

Yang/
Clark

In Prep

  ASC, Nov. 2002

66

Yang, Bin

 

Clin. Fellow

Cyto

Clark & Rosenthal

Clinical

 

Detection of Promoter Methylation of Tumor Suppressor Genes in Hepatoblastoma Using Methylation-Specific PCR.

Yang/
Clark

In Prep

  ASC, Nov. 2002

67

Yang, Bin

 

Clin. Fellow

Cyto

Clark & Rosenthal

Clinical

 

Promoter Methylation Profiling of Tumor Suppressor Genes in Hepatic Adenoma and Focal Nodular Hyperplasia.

Yang/
Clark

In Prep

  USCAP Annual Mtg.

68

Yang,
Rongcun

 

Res. Fellow

Gyn

Roden

Basic

 

Activation of Splenic CD8a+CD11C+ Dendritic Cells by Papillomavirus-like Particles to Produce Interferon-y and Induce Th1 Responses.

Yang/
Roden

In Prep

Jnl. of Experimental Medicine

USCAP Annual Mtg.

69

Yuan, Bibo

 

Res. Fellow

Mol. Path.

Gabrielson

Basic

 

Increased Expression of Mitotic Checkpoint Genes in Breast Cancer Cells with Chromosomal Instability.

Yuan/
Gabrielson

 

 

 

70

Zhang,
Shengle

 

Res. Fellow

Mol. Diag.

Berg

Clinical

 

Ig VH Somatic Mutation Identification in Chronic Lymphotic Leukemia.

Zhang/ Berg

Yes

Jnl of Mol Diag, 4:244A, 2002

AMD

71

Zhou,
Ming

 

Clin. Fellow

Surg Path

Epstein

Clinical

 

Expression and Diagnostic Utility of Alpha-Mehtylacyl-CoA-Racemase (P504S) in Foamy Gland and Pseudohyperplastic Prostate Cancer.

Zhou/
Epstein

In Press

AJSP

USCAP Annual Mtg.

72

Mosse,
Claudio

 

Housestaff

Path

Epstein

Clinical

 

The Prognostic Significance of the Tertiary Gleason Pattern 5 in Radical Prostatectomy Specimens.

Mosse/
Epstein

 

 

USCAP Annual Mtg.


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