2011 Pathology Young Investigators' Day Awards


13th ANNUAL DEPARTMENT OF PATHOLOGY YOUNG INVESTIGATORS' DAY
April 6, 2011

Congratulations to the Award Recipients
Basic: Samarjit Das, Ph.D.
Clinical: Ashley Cimino-Mathews, M.D.
Translational: Sonal Gupta, Ph.D.
Excellence in BASIC RESEARCH
Presenter Title Division Senior Author Poster Title
Timothy Babatz, B.S. Graduate Student Hematologic Pathology Kathleen H. Burns, M.D., Ph.D. Discovering retrotransposon insertion polymorphisms (RIPs) associated with human phenotypes by TIP-chip
Jobert G. Barin, Ph.D. Research Fellow Immunologic Pathology Noel R. Rose, M.D., Ph.D. IL17A switches from a pathogenic to a protective function in experimental autoimmune myocarditis in the absence of IFNγ
Yen-Ling Chiu, M.D. Graduate Student Immunologic Pathology Jonathan P. Schneck, M.D., Ph.D. Regulation of functional avidity and polyfunctionality in human antigen-specific CTLs
Jewel A. Daniel, Ph.D. Research Fellow Oncology Edward W. Gabrielson, M.D. High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells
Samarjit Das, Ph.D. Research Fellow Cardiologic Pathology Charles Steenbergen, M.D., Ph.D. Existence of microRNA, "mito-miR-181c", in Heart-Derived Mitochondria: Role in regulation of mitochondrial function by targeting mt-COX1
Bin Guan, Ph.D. Research Fellow GYN Pathology Ie Ming Shih, M.D., Ph.D. The Tumor Suppressor Role of ARID1A
AeRyon Kim, Ph.D. Research Fellow Immunologic Pathology Scheherazade Sadegh-Nasseri, Ph.D. Presentation of immunodominant epitopes from mixture of protein antigens is hierarchial
Cheryl M. Koh, B.S. Graduate Student Urologic Pathology Angelo M. DeMarzo, M.D., Ph.D. Alterations in Nucleolar Structure and Gene Expression Programs in Prostatic Neoplasia are Driven by the MYC Oncogene
Mark J. Kohr, Ph.D. Research Fellow Cardiologic Pathology Charles Steenbergen, M.D., Ph.D. Resin-Assisted Capture Methods show that S-nitrosylation Exerts Cardioprotection During Ischemia/Reperfusion Injury by Directly Reducing Cysteine Oxidation
Yuri Poluektov, B.S. Graduate Student Immunologic Pathology Scheherazade Sadegh-Nasseri, Ph.D. The effects of HLA-DO on peptide binding by MHC Class II HLA-DR1
Alexander Stoeck, Ph.D. Research Fellow GYN Pathology Ie Ming Shih, M.D., Ph.D. Identification and characterization of novel Notch3 interacting proteins in ovarian cancer
Chapman M. Wright, Ph.D. Research Fellow GI/Liver Pathology James R. Eshleman, M.D., Ph.D. A hypoxia-activated protein switch as a potential anti-cancer therapeutic
Chao-Yi Wu, M.D. Graduate Student GYN Pathology T.C. Wu, M.D., Ph.D. Intraperitoneal administration of poly (I:C) with polyethylenimine leads to significant antitumor immunity against murine ovarian tumor
Kai Lee Yap, B.Sc. Graduate Student GYN Pathology Ie Ming Shih, M.D., Ph.D. Identification and Characterization of NAC1 as a Profilin 1/Actin-binding Protein that Ensures Effective Cytokinesis in Cancer Cells

Excellence in CLINICAL RESEARCH
Presenter Title Division Senior Author Poster Title
Ashley Cimino-Mathews, M.D. Housestaff Surgical Pathology Pedram Argani, M.D. Androgen Receptor Expression in Usually Maintained in Initial Surgically-Resected Breast Cancer Metastases, But Often Lost in Terminal Metastases Found at Autopsy
Mamta Gupta, M.D. Clinical Fellow GYN Pathology Brigitte M. Ronnett, M.D. Diagnostic reproducibility of hydatidiform moles: molecular genotyping significantly improves morphologic assessment
Delicia Munfus-McCray, Ph.D. Housestaff Cytopathology Qing Kay Li, M.D., Ph.D. KRAS and EGFR mutational rate, discordance and outcome analysis in metastatic lung adenocarcinomas in comparison to primary lung adenocarcinoma. A retrospective study of 344 cases.

Excellence in TRANSLATIONAL RESEARCH
Presenter Title Division Senior Author Poster Title (pdf)
Kerstin E. Braunstein, Ph.D. Research Fellow Neurologic Pathology Philip C. Wong, Ph.D. Mice expressing a mutant dynactin gene (DCTN1) identified in sporadic ALS exhibit evidence of motor neuron disease
Katie K. Brennan, D.V.M. Graduate Student Molecular Pathology Joseph L. Mankowski, D.V.M. Cardiac Dysfunction Associated with Myocardial Viral Load in SIV-Infected Macaques can be Prevented by CCR5 Inhibitor Maraviroc
Sonal Gupta, Ph.D. Research Fellow GI/Liver Pathology Anirban Maitra, M.B.B.S. Molecular Determinants of Retinoic Acid Sensitivity in Pancreatic Cancer
Christopher M. Heaphy, Ph.D. Research Fellow Genitourinary Pathology Alan K. Meeker, Ph.D. Prevalence of Alternative Lengthening of Telomeres (ALT) in Human Cancer Subtypes
Tory Johnson, M.S. Graduate Student Neurologic Pathology Avindra Nath, M.D. HIV Tat protein activates Th-17 cells in a TCR independent manner: A potential role in chronic immune activation
Elisabetta Kuhn, M.D. Research Fellow GYN Pathology Ie Ming Shih, M.D., Ph.D. The diagnostic and biological implications of laminin expression in serous tubal intraepithelial carcinoma
Kihyuck Kwak Graduate Student GYN Pathology Richard B.S. Roden, Ph.D. Evaluation of an L2 multimervaccine against diverse oncogenic HPV types
Brent A. Orr, M.D., Ph.D. Housestaff Neurologic Pathology Charles G. Eberhart, M.D., Ph.D. YAP1 is widely expressed in human brain tumors and promotes glioblastoma growth