2014 Pathology Young Investigators' Day Awards


16th ANNUAL DEPARTMENT OF PATHOLOGY YOUNG INVESTIGATORS' DAY
April 3, 2014

Top Three Presenters in their Category
Basic: Martin Samuel Taylor
Clinical: Genevieve M. Crane, M.D., Ph.D.
Translational: Ulf D. Kahlert, Ph.D.
Excellence in BASIC RESEARCH
Presenter Title Division Senior Author Poster Title
Martin Samuel Taylor Medical Student Hematologic Pathology Kathleen Burns, M.D., Ph.D. Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition.
David Nauen, M.D., Ph.D. Housestaff Neuropathology Liam Chen, M.D., Ph.D. Amygdalar Astrocytic Alpha-synuclein Aggregates in Lewy Body Disease
Sheng Wang, Ph.D. Research Fellow Neuropathology Liam Chen, M.D., Ph.D. Study Glia-Mediated Neurodegeneration in Parkinson Disease
Gretchen Hubbard, Ph.D. Research Fellow Kidney/GU Pathology Karen S. Sfanos, Ph.D. MYC overexpression combined with Pten loss generates genomic instability and rapid metastasis in a new mouse model of lethal prostate adenocarcinoma
Maria Noel Martina Lingua, M.D. Research Fellow Immunopathology Abdel Rahim A. Hamad, D.V.M., Ph.D. Analysis of kidney double negative (CD4-/CD8-) αβ T Cells in the steady state and acute kidney injury
Yuri O. Poluektov, B.S. Graduate Student Immunopathology Scheherazade Sadegh-Nasseri, Ph.D. MHC Class II accessory molecule HLA-DO can skew the selection of immunodominant peptide epitopes from an antigenic protein
Jillian Legault, M.S. Graduate Student Immunopathology Noel R. Rose, M.D., Ph.D. The dual role of IL6 in priming autoimmune myocarditis and driving inflammatory dilated cardiomyopathy
Maria Elisa Perez-Munoz, Ph.D. Research Fellow Immunopathology Daniel Peterson, M.D., Ph.D. Discordance Between Changes in the Gut Microbiota and Pathogenicity in a Mouse Model of Spontaneous Colitis

Excellence in CLINICAL RESEARCH
Presenter Title Division Senior Author Poster Title
Genevieve M. Crane, M.D., Ph.D. Housestaff Surgical Pathology Amy Duffield, M.D., Ph.D. Clinical and Phenotypic Features of Primary CNS Lymphoproliferative Disorders Arising in the Context of Immunosuppressive Treatment
Guoli Chen, M.D., Ph.D. Housestaff Molecular Genetics James R. Eshleman, M.D., Ph.D. Cytosine Deamination Is The Major Cause of Baseline Noise in Next Generation Sequencing
Christopher VandenBussche, M.D., Ph.D. Clinical Fellow Surgical Pathology Pedram Argani, M.D. Reflex ER/PR/Her2 Analysis of Breast Cancers in Core Needle Biopsy Specimens Significantly Increases Health Care Costs
Brittany Holmes, M.D. Housestaff Immunopathology Anna Yemelyanova, M.D. Napsin A: A Sensitive Immunohistochemical Marker for Uterine Clear Cell Carcinoma
Athena Kantartzis Petrides, Ph.D. Clinical Fellow Clinical Chemistry Mark Marzinke, Ph.D. Development and Validation of a Robust Tandem LC-MS/MS Method for the Quantification of Antidepressants in Serum
Nathaniel Smith, M.D. Housestaff Surgical Pathology Pedram Argani, M.D. Smooth Muscle and Renal Tubulopapillary Epithelial Tumor (SMARTPET): A Distinctive Biphasic Renal Neoplasm
Iris Chen, B.S. Graduate Student Transfusion Medicine Susan H. Eshleman, M.D., Ph.D. Antiretroviral Drug Resistance Among HIV-infected Black Men Who Have Sex With Men in the US

Excellence in TRANSLATIONAL RESEARCH
Presenter Title Division Senior Author Poster Title
Ulf D. Kahlert, Ph.D. Research Fellow Neuropathology Charles Eberhart, M.D., Ph.D. ZEB1 Is Expressed In Neoplastic And Non-Neoplastic Neural Stem Cells And Required For Glioblastoma Invasion
Alexander S. Baras, M.D., Ph.D. Housestaff Surg/Molecular Pathology George Netto, M.D. Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Chemotherapy in Muscle Invasive Urothelial Carcinoma
Fnu Yuyu, Ph.D. Research Fellow GYN Pathology Ie Ming Shih, M.D., Ph.D. Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-induced Cytotoxicity by Stabilizing Microtubule
Ren-Chin Wu, M.D. Graduate Student GYN Pathology Ie Ming Shih, M.D., Ph.D. Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynecologic malignancies
Allison Hanaford, B.S. Graduate Student Neuropathology Charles Eberhart, M.D., Ph.D. Targeting glutamine metabolism as a therapeutic strategy in MYC-driven medulloblastoma
Joshua Weiyuan Wang, B.Sc. Graduate Student OB/GYN Pathology Richard Roden, Ph.D. Measurement of neutralizing serum antibodies of patients vaccinated with human papillomavirus L1 or L2-based immunogens using furin-cleaved HPV pseudovirions
Harpreet Kaur, Ph.D. Research Fellow Neuropathology Charles Eberhart, M.D., Ph.D. HMGA2 promotes invasion and stemness in glioblastoma
Anne Macgregor-Das, B.S. Graduate Student GI Pathology Chris Iacobuzio-Donahue, M.D. The Role of Immunosuppressive Cells in Pancreatic Cancer Metastasis
Christian Schuetz, Ph.D. Research Fellow Immunopathology Jonathan P. Schneck, M.D., Ph.D. Antigen-specific T cell Redirectors (ATR): a nanoparticle based approach for antigen-specific redirection of T cells to tumors
Ajay Vaghasia, B.S. Lab Tech Urologic Oncology Angelo DeMarzo, M.D., Ph.D. Effect of block age of formalin-fixed paraffin embedded tissue blocks on gene expression measures and its impact on translational research
Chad M. McCall, M.D., Ph.D. Clinical Fellow Hematologic Pathology James R. Eshleman, M.D., Ph.D. False-Positive Mutations from Mispriming Events in Next Generation Sequencing Have Unique Signatures