Department of Pathology Young Investigators' Day

18th Annual Department of Pathology Young Investigators' Day
March 30, 2016

Top Three Presenters in their Category
*Basic: Nelson Song, B.S. and Jonathan Ling, B.S.
Clinical: Lisa Rooper, M.D.
Translational: Michael Haffner, M.D., Ph.D.
*Two Basic Top Presenter Awards given due to tie ratings

Excellence in BASIC RESEARCH
Presenter Title Division Senior Author Poster Title
Nianbin (Nelson) Song, B.S. Graduate Student
Immunology Scheherazade Sadegh-Nasseri MHC class II antigen-processing chaperone H2-O shapes CD4 T cell receptor repertoire
Jonathan Ling, B.S. Graduate Student
Neuropathology Phil Wong, Ph.D. PTBP1 and PTBP2 are cryptic exon repressors
Mindy Kim Graham, Ph.D. Research Fellow GU Pathology Alan Meeker and
Christopher Heaphy
Generating and characterizing novel prostate cancer cell lines that employ the Alternative Lengthening of Telomeres (ALT) telomere maintenance
Tatsuo Hata, M.D. Research Fellow GI/Liver Pathology Michael Goggins Cyst fluid telomerase activity predicts the histologic grade of cystic neoplasms of the pancreas
Rosie Jiang, B.S. Graduate Student
GYN Pathology Richard Roden Spontaneous and vaccine-induced clearance of Mus Musculus Papillomavirus1 (MusPV1) infection
Byunghak Kang, D.V.M. Graduate Student
Oncology Stephen Baylin Oncogenic BRAFV600E drives stem cell niche factors independent growth and tumorigenic transformation in colon organoids
Chih-Ping Mao, B.S. Graduate Student
GYN Pathology TC Wu Release of self-DNA underlies the adjuvant effect of chemotherapy and facilitates synergy between antigen-specific vaccination and immune checkpoint blockade
Yoshihisa Matsushita, Ph.D. Research Fellow GI/Liver Pathology James Eshleman Improved differentiation and chemoresponses of pancreatic adenocarcinoma in hanging drop culture
Youngran Park, B.S. Graduate Student
GYN Pathology Ie-Ming Shih and
Tian-Li Wang
The caretaker role of ARID1A, a chromatin remodeling protein, in DNA repair and cancer development
Corey M. Porter, B.S. Graduate Student
Kidney/GU Pathology Karen Sfanos The Induction and Silencing of Lactoferrin, a Putative Prostate Cancer Tumor Suppressor Gene, in the Early Stages of Prostate Neoplasia and Progression
Bo-Yi Sung, M.D. Graduate Student
Immunopathology Jonathan Schneck Wnt Signaling Induces Polyfunctional Human CD8+ T Cells Associated with PRMTs Expression
Robin A. Welsh, M.S. Graduate Student
Immunopathology Scheherazade Sadegh-Nasseri Exploring a possible role for the MHC Class II accessory molecule H2-O in the development of experimental autoimmune encephalomyelitis
Presenter Title Division Senior Autor Poster Title
Lisa Rooper, M.D. Housestaff Surgical Pathology Ashley Cimino-Mathews Identifying Targets for Reducing Immunohistochemical Utilization: an Audit of 18,760 Cases
Allison B. Chambliss, M.D. Clinical Fellow Clinical Chemistry Mark Marzinke Rapid Screening for Targeted Genetic Variants via High-Resolution Melting Curve Analysis
Genevieve M. Crane, M.D., Ph.D. Clinical Fellow Hematologic Pathology Amy Duffield Macrophages in Post-Transplant, Relapsed Classical Hodgkin Lymphoma are Donor-Derived
Thomas J. Gniadek, M.D., Ph.D. Housestaff Transfusion Medicine Karen King Passenger Lymphocyte Syndrome Due to Anti-D: Diagnosis, Clinical Course and Quantitative Analysis of Hemolysis
Armen Khararjian, M.D., M.B.A. Housestaff Surgical Pathology Alex Baras The utility of intraoperative gross examination of colorectal resections: a retrospective review of 200 sequential cases
Emily R. Nelson, M.D. Housestaff Surgical Pathology Ashley Cimino-Mathews Reactive Squamous Metaplasia in the Breast: A 20-Year Review with Emphasis on Features Distinguishing Benign Metaplasia from Malignant Lesions
Elizabeth Thompson, M.D., Ph.D. Housestaff Surgical Pathology Ashley Cimino-Mathews PD-L1 Expression and the Immune Microenvironment in Primary Invasive Lobular Carcinomas of the Breast
Kevin M. Waters, M.D., Ph.D. Housestaff Cardiac/Autopsy Pathology Marc Halushka Implementation of the New AECVP/SCVP Aorta Consensus Grading Scheme
Presenter Title Division Senior Autor Poster Title
Michael C. Haffner, M.D., Ph.D. Housestaff Kidney/GU Pathology Angelo DeMarzo Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular
Javier A. Baena-Del Valle, M.D. Research Fellow Kidney/GU Pathology Angelo DeMarzo Human telomerase RNA component (hTR/TERC) is consistently overexpressed in prostate cancer, required for cell proliferation and is positively regulated by MYC (c-Myc)
Jacqueline A. Brosnan-Cashman, Ph.D. Research Fellow GU Pathology Alan Meeker ALT-positive pediatric high grade glioma cells display chemosensitivity to ATR pathway inhibition
Marija Debeljak, B.S. Laboratory Tech
(functions as student)
GI/Liver Pathology James Eshleman Observed Haplotypes in Three Populations for Five Loci
Nicola Diny, M.S. Graduate Student
Immunopathology Daniela Cihakova The eotaxin-CCR3 pathway recruits eosinophils to the heart during eosinophilic myocarditis
Allison R. Hanaford, B.S. Graduate Student
Neuropathology Charles Eberhart DiSCoVERing innovative therapies for rare tumors: Combining genetically accurate disease models with advanced in silico analysis to identify novel therapeutic targets
Heidi A. Hempel, B.S. Graduate Student
Kidney/GU Pathology Karen Sfanos Low Intratumoral Mast Cell Number and Density are Associated with a Higher Risk of Prostate Cancer Recurrence
Harpreet Kaur, Ph.D. Research Fellow Neuropathology Charles Eberhart The transcriptional modulator HMGA2 promotes glioblastoma tumorigenicity and increases sensitivity to ATR inhibitors
Brad A. Poore, B.S. Graduate Student
GI/Liver Pathology Anne Le Nanotechnology-enhanced delivery of a glutaminase inhibitor: new treatment for pancreatic cancer
Samantha L. Semenkow, B.Sc. Graduate Student
Neuropathology Charles Eberhart Immune co-stimulatory blockade permits human glioblastoma xenografting in immunocompetent mice: model validation with MRI and bioluminescence imaging
Shisheng Sun, Ph.D. Research Fellow Clinical Chemistry Hui Zhang Comprehensive analysis of protein glycosylation using N-linked glycans and glycosite-containing (NGAG) method