Department of Pathology Young Investigators' Day

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22nd Annual Department of Pathology Young Investigators' Day
(March 18th event cancelled due to COVID-19)
May 2020


Top Three Presenters in their Category
Basic: Mohanraj Sadasivam, Ph.D.
Clinical: John Lin, B.S.
Translational: David Clark, Ph.D.

Excellence in BASIC RESEARCH

Presenter Title Division Senior Author Poster Title
Mohanraj Sadasivam, Ph.D. Res Fellow Immunopathology Abdel Rahim A Hamad, DVM, Ph.D. A mutually beneficial relationship between double-negative (DN) T cells and renal epithelial cells explains selective accumulation of DN T cells in the kidney
Rizan Ahmed, Ph.D. Res Fellow Immunopathology Abdel Rahim A Hamad, DVM, Ph.D. Role of X cell-secreted mAb (x-mAb) in the pathogenesis of Type 1 Diabetes (T1D)
Tianyu Cao, B.M. Grad Stud
(Trainee)
Neuropathology Philip C-Y Wong, Ph.D. Validation of TDP-43 splicing repression as a therapeutic strategy for ALS- Frontotemporal Dementia
Zahra Omidian, DVM, Ph.D. Res Fellow Immunopathology Abdel Rahim A Hamad, DVM, Ph.D. An unexpected role for x-mAb in inducing anti-insulin antibodies; provides new insights into T1D mechanism
J. David Peske, M.D., Ph.D. Housestaff Immunopathology Nilabh Shastri Shaping of the peptide-MHC Class I repertoire by human ER aminopeptidases
Taejoon Won, Ph.D. Res Fellow Immunopathology Daniela Cihakova, M.D., Ph.D. Autoimmunity against Cardiac Self-Antigen Drives Immune Checkpoint Inhibitor-Associated Myocarditis Development
Megan Wood, B.S. Grad Stud
(Molec Microbio & Immunol)
Immunopathology Daniela Cihakova, M.D., Ph.D. PD-L1 on macrophages protects from severe collagen induced arthritis in females



Excellence in CLINICAL RESEARCH

Presenter Title Division Senior Author Poster Title
John Lin, B.S. Res Asst GI/Liver Pathology James R. Eshleman, M.D., Ph.D. Improved microsatellite instability detection in endometrial and prostate cancers using long mononucleotide repeat markers
Rajeswari Jayakumar, M.D. Clin Fellow Heme Path Amy S. Duffield, M.D., Ph.D. Pathologic Findings in Patients with Refractory B-Lymphoblastic Leukemia Treated with Blinatumomab



Excellence in TRANSLATIONAL RESEARCH

Presenter Title Division Senior Author Poster Title
David Clark, Ph.D. Res Fellow Clinical Chemistry Hui Zhang, Ph.D. Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
Jiayu Chen, B.A. Grad Stud
(CMM)
GU Pathology Angelo DeMarzo, M.D., Ph.D. An in situ atlas of mitochondrial DNA in mammalian tissues reveals high content in stem/progenitor cells
Nicolas Giraldo-Castillo, M.D., Ph.D. Housestaff Surgical Pathology Kathleen Burns, M.D., Ph.D. Transposable Elements and the Tumor Immune Landscape in Human Cancer
Ariel Isser, B.S. Grad Stud
(BME)
Immunopathology Jonathan P. Schneck, M.D., Ph.D. A Nanoparticle Platform to Expand Antigen Specific CD4+ T cells for Cancer Immunotherapy
Janielle Maynard, Ph.D. Res Fellow Kidney/GU Pathology Karen Sfanos, M.S., Ph.D. Targeting P2X4 Purinergic Receptors in Aggressive Prostate Cancer
Stefano Negri, M.D. Res Fellow Surgical Pathology Aaron James, M.D., Ph.D. Human perivascular stem cells prevent bone graft resorption in osteoporotic contexts by inhibiting osteoclast formation
Khoa Pham, M.D. Res Fellow Neuropathology Eric Raabe, M.D., Ph.D. Novel prodrug of 6-diazo-5-oxo-l-norleucine suppresses MYC-driven medulloblastoma growth and induces apoptosis
Yangying Zhou, M.D. Med Stud Clinical Chemistry Qing Kay Li, M.D., Ph.D. Mapping Human Cancers using Mass Spectrometry-based Data Independent Acquisition (DIA). A Tissue-based Global Proteomic Analysis