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The Neuropathology Division is recognized internationally for its research, diagnosis, and consultations on disorders of the brain and central nervous system. Pathologists, physicians and medical examiners from around the world contact us for diagnosis of tumors and traumatic lesions of the brain and spinal cord, forensic neuropathology, neurodegenerative disorders, and progressive neurologic diseases in children. We consult with pathologists and referring physicians on issues related to patient care and can also provide guidance to family members on disorders with a genetic component.


specimens contact:

Fausto Rodriguez, M.D.
Director, Clinical Neuropathology Service

Johns Hopkins University School of Medicine
Sheikh Zayed Tower, Room M2101
1800 Orleans Street
Baltimore, MD 21231

Phone: 410-955-8378
Fax: 410-614-9310


Neuropathology was established as a separate subspecialty in the Department of Pathology in 1971under the leadership of Dr. Donald L. Price. The division gained an international reputation for its experimental studies of diseases of the brain, in particular Alzheimer's and other neurodegenerative diseases. Ongoing experience with state-of-the-art neuropathology research ensures that faculty members remain at the forefront of their fields, with access to the most recent methodologies for diagnosis and continuing experience with many cases of unusual diseases.

Our diagnostic expertise in neuropathology includes adult and pediatric brain and spinal cord tumors, cerebrovascular disease, trauma, forensic neuropathology, AIDS; and neurodegenerative diseases such as Alzheimer's, Parkinson's, progressive supranuclear palsy (PSP), Huntington's disease, and amyotrophic lateral sclerosis (ALS).

Special capabilities and services

Our laboratory is fully equipped to perform the special diagnostic tests needed to study neoplastic and degenerative diseases of the brain, and has vast experience doing the special stains required for these studies. We are skilled in interpreting stereotactic needle biopsies of brain lesions and can perform in-situ hybridization, immunohistochemistry, light microscopy, immunofluorescence, and electron microscopy, as necessary.

IMPORTANT NOTE - Unstained Slides Requirement
Note that all tissue (unstained slides) must be submitted on a plus charged slide. The Immunopathology Laboratory recommends a white plus charged slide that is available from Cardinal Health. The catalogue number for the white plus slide is M6159-6, however one must specify to the vendor whether to order as one gross (pack of 144 slides), one case (10 packs per case).

Timely Results

The consultation service aims to respond to requests within 24 hours of the receipt of material. Dr. Fausto Rodriguez is available for any questions and discussions related to surgical neuropathology cases, including advice related to ancillary immunohistochemical and molecular testing. Dr. Rodriguez personally provides a verbal report to the requesting physician and/or sends the final report by fax. Pathology materials can be returned, if requested.

Written reports on post-mortem evaluations are generally provided within four weeks. The final written report is sent by mail. Dr. Juan Troncoso is also available for phone consultation. Autopsy specimens are returned promptly upon request.

Surgical specimens will be returned promptly after the evaluation and report are completed.