Phone: 1-800-997-5475 | Fax: 410-367-2404 | Email: apresco1@jhmi.edu

Get a Second Opinion


Why Get a Pathology Second Opinion?

Numerous publications show the clinical and economic benefits of obtaining a second opinion for Pathology specimens. Obtaining a second opinion in Pathology can in a small percent of cases lead to a complete change in diagnosis in a wide range of conditions including non-cancerous growths, inflammatory disorders, infections, and cancer. In terms of cancer, changes can be from cancer to benign (or vice versa) or from one type of cancer to another, which could have a significant impact on treatment and prognosis. A second review of Pathology more frequently also brings changes to the cancer grade or stage, which can affect prognosis as well as therapy. Jonathan Epstein, M.D.
Director of Surgical Pathology
View Pathology Consult Brochure Our experience speaks for itself Our pathologists at work



What you need to do:




  1. 1.

    Before you start, ask your insurance company:
    1. Do they require pre-authorization for a second opinion?
    2. Do they require you to submit a second opinion through your doctor? (If so, choose 'Send Slides Through Your Doctor' below)
    More Insurance Details

  2. 2.

    Request the following from your doctor:
    - pathology slides
    - pathology report

  3. 3.

    Package your slides carefully to avoid breakage
    How To Package Your Slides

  4. 4.

    Also include:
    - Copy of insurance card— front and back.
    - Second Opinion Request Form, completed.

  5. 5.

    Ship via Fedex or UPS
    Use only a signature-required courier. No U.S. Mail.
    Where to send your slides
    For your convenience: Fedex shipping services

  6. 6.

    Final report with diagnosis will be faxed to your doctor.
    Upon request, an ecrypted email with diagnosis can also be sent to you.
    Usually, a diagnosis is reached within 3-5 days of your slides' arrival at Johns Hopkins. If there's a delay, please contact the consult office.





  1. 1.

    Before you start, ask your insurance company if they require you to submit a second opinion through your doctor. If so, you will need to indicate that below.
    If this is not a requirement, it may be easier for you to contact the Pathology department of your hospital directly and ask them to follow the directions below.
    More Insurance Details

  2. 2.

    Request that your doctor package the following:
    - Pathology slides
    - Pathology report
    - Pertinent clinical information or Pathology Consultation Request Form
    - Copy of insurance card—front and back
    - Form from doctor to indicate that he is requesting a second opinion (optional: submit this only if you answered "yes" to #1 above.)

    This sample request letter includes all the information that your doctor may need.

  3. 3.

    Request that your doctor ship your slides to Johns Hopkins Pathology
    Where to send your slides
    When we receive your slides, we will send your doctor a confirmation fax.

  4. 4.

    Final report with diagnosis will be faxed to your doctor.
    Upon request, an ecrypted email with diagnosis can also be sent to you.
    Usually, a diagnosis is reached within 3-5 days of your slides' arrival at Johns Hopkins. If there's a delay, please contact the consult office.





Consult Fees

Slides only (most cases):$250
Slides and blocks:$350

In some cases, additional testing may be required. Associated fees may be incurred up to $1,800 in a minority of more complicated cases requiring special studies.



Meet Our Consult Physicians






Optional: You may request that your case be seen by a specific pathologist on the forms that you send with your slides.


More Insurance Details

For questions about insurance coverage, please call the Billing Office at (410)-933-1306.


  • Out-of-state Medicaid: Due to state regulations Johns Hopkins Pathology can not bill Medicaid outside of the state of Maryland.

  • Out-of-state Blue Shield: Effective October 2013, National Blue Shield mandates reference lab claims be filed to the Blue carrier in which the referring physicians NPI is currently registered and the claim is consider out of network. JHU Pathology billing will file the claim to the appropriate carrier and send a self pay statement to the patient.

  • Cases billed to patient: When pre-authorization is required and not obtained the requesting party will be billed.

Where to Send Your Slides

Surgical Pathology Slides

Johns Hopkins Medical Laboratories
1620 McElderry Street
Reed Hall Room 315
Baltimore, MD 21205
Phone: 410-955-2405
Fax: 410-367-2404


Cytopathology Slides

The Johns Hopkins Hospital
600 N Wolfe Street
Cytopathology Consult Service
Pathology, Room 412D
Baltimore, MD 21287-6940
Phone: 410-955-3520
Fax: 410-955-3438


Dermatopathology Slides

For all dermatopathology-related information, please visit the Johns Hopkins Dermatopathology site.


Contact the Consult Office

Phone: 1-800-997-5475 (to confer with faculty or for processing/billing inquiries)

Fax: 410-614-7712

Email: apresco1@jhmi.edu