Graduate Program in Pathobiology

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News and Announcements

Pathobiology Thesis Seminar
Monday, September 24, 2018 - 12:00 pm
Speaker: Corey Porter (Ph.D. Candidate)
Title: The Induction and Silencing of Lactoferrin, a Putative Prostate Cancer Tumor Suppressor Gene, in the Early Stages of Prostate Neoplasia and Progression
Place: Mountcastle Auditorium
Advisor: Dr. Karen Sfanos

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Congratulations, Audrey Knight!

We are proud to announce that Audrey Knight, a 3rd year graduate student in the Pathobiology Graduate Program, has been awarded an R25 pilot grant from the NIMH titled: "Dysregulation of central nervous system glial immune responses in a cART-suppressed SIV/macaque model of chronic HIV CNS disease."

Audrey Knight is from St. Louis, Missouri and received her Bachelors of Science degree in biology from Illinois College in 2014. While at Illinois College, she conducted several independent research projects focusing on RNA interference, synthetic chemistry, virology, and orchid conservation. Audrey joined the lab of Joseph Mankowski, DVM, PhD, DACVP, in 2016 where she studies the role of microglia in HIV associated neurocognitive disorders (HAND) using an SIV/macaque model.

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Congratulations, Hee Sun Choi!

We are proud to announce that Hee Sun Choi, a graduate student in the Pathobiology Graduate Program, has been awarded the MAA Winter 2016 Predoctoral Fellowship. The 2-year award was granted to Hee Sun by the Research Committee of the American Heart Association to fund her project: Role of group 2 innate lymphoid cells in eosinophilic pericarditis.

Hee Sun Choi was born in Seoul, South Korea and received her Bachelor and Master of Science degrees in Biotechnology from Yonsei University in 2009 and 2011, respectively. While at Yonsei University, the main focus of her research was protein folding. Hee Sun joined the laboratory of Daniela Cihakova, M.D., Ph.D., and has been studying the mechanism of the development of pericarditis-inflammation in the heart. Her long term goal is to contribute to developing more effective ways to prevent and treat human diseases.

Pathobiology Thesis Seminar
Tuesday, May 8, 2018 - 1:00 pm
Speaker: Wan Rou Yang (Ph.D. Candidate)
Title: Developing SQuIRE to map the landscape of interspersed repeat expression
Place: Darner Conference Room
Advisor: Dr. Kathy Burns

Pathobiology Thesis Seminar
Tuesday, March 27, 2018 - 2:00 pm
Speaker: Jaeyeun Lee (Ph.D. Candidate)
Title: An antibiotic triggers cell stress responses and Epstein-Barr virus lytic activation
Place: CRB I, 3M42
Advisor: Dr. Richard Ambinder

Pathobiology Thesis Seminar
Friday, March 23, 2018 - 2:30 pm
Speaker: Bradley Poore (Ph.D. Candidate)
Title: Inhibition of Glutamine Metabolism Sensitizes Cancer to Further Pharmacological Disruption and Yields Clinically Viable Treatment Options
Place: Wood Basic Science Auditorium, PCTB/WBSB Ground Level
Advisor: Dr. Eric Raabe

Pathobiology Thesis Seminar
Friday, March 16, 2018 - 2:00 pm
Speaker: Michael E. Urbanowski (Ph.D. Candidate)
Title: Studies on the Mechanism and Inhibition of Tuberculosis Cavitation
Place: Mountcastle Auditorium, PCTB
Advisor: Dr. William Bishai

Pathobiology Thesis Seminar
Monday, November 27, 2017 - 3:30 pm
Speaker: Heidi Hempel
Ph.D. Candidate
Title: The Role of Mast Cells in Prostate Cancer Initiation and Recurrence
Place: Mountcastle Auditorium, PCTB
Advisor: Dr. Karen Sfanos

Pathobiology Thesis Seminar
Tuesday, September 12, 2017 - 3:15 pm
Speaker: Carolyn Tallon
Ph.D. Candidate
Title: BACE1 activity levels inversely influence peripheral axon regeneration: a potential therapy for nerve injuries and diseases
Place: Rangos 490
Advisor: Dr. Mohamed Farah

Pathobiology Thesis Seminar
Monday, July 17, 2017 - 3:00 pm
Speaker: James Pendleton
Ph.D. Candidate
Title: Mechanisms of Chondroitin Sulfate Proteoglycan (CSPG) Mediated Inhibition of Oligodendrocyte Function and Myelination
Place: Kennedy Kreiger Institute Outpatient Center
801 N. Broadway, Room 202
Advisor: Dr. Visar Belegu

Pathobiology Thesis Seminar
Monday, July 10, 2017 - 1:30 pm
Speaker: Breann Yanagisawa
Ph.D. Candidate
Title: Identifying Novel Therapeutic Targets in Acute Myeloid Leukemia
Place: CRB II, Rm 111
Advisor: Dr. Rick Jones

Pathobiology Thesis Seminar
Wednesday, June 14, 2017 - 12:00 noon
Speaker: Youngran Park
Ph.D. Candidate
Title: The Caretaker Role of ARID1A in DNA Repair and The Effects of Targeted Therapy in ARID1A Mutated Cancers
Place: CRB II, Rm 111
Advisors: Dr. Ie-Ming Shih and Dr. Tian-Li Wang

Pathobiology Thesis Seminar
Tuesday, June 13, 2017 - 3:00pm
Speaker: Samantha Semenkow
Ph.D. Candidate
Title: Targeting the Notch Pathway and the Role of the Tumor Microenvironment in Glioblastoma
Place: PCTB West Lecture Hall
Advisors: Dr. Charles Eberhart

Pathobiology Thesis Seminar
Monday, April 10, 2017 - 12:00 noon
Speaker: Rosie Jiang
Ph.D. Candidate
Title: Therapeutic Vaccine and Drug Development for Gynecologic Cancer
Place: Owens Auditorium (between the CRB's)
Advisors: Dr. Richard Roden

Pathobiology Thesis Seminar
Thursday, April 6, 2017 - 4:00 pm
Speaker: Jonathan Ling
Ph.D. Candidate
Title: The Role of Cryptic Exon Repression in Neurogenesis and Neurodegeneration
Place: Darner Conference Room (across from Turner fountain)
Advisors: Dr. Philip Wong

Pathobiology Thesis Seminar
Tuesday, March 28, 2017 - 2:00 pm
Speaker: Allison Hanaford
Ph.D. Candidate
Title: Using a novel human neural stem cell model of aggressive medulloblastoma to investigate new therapeutic strategies
Place: Mountcastle Auditorium, PCTB
Advisors: Dr. Charles Eberhart and Dr. Eric Raabe

Pathobiology Thesis Seminar
Monday, March 20, 2017 - 4:00 pm
Speaker: Meng Su
Ph.D. Candidate
Title: Role of Cytochrome P450 Enzymes in the Acute Myeloid Leukemia Bone Marrow Microenvironment
Place: CRB I, Rm. 3M42
Advisor: Dr. Richard Jones

Pathobiology Thesis Seminar
Speaker: Bo-Yi Sung
Ph.D. Candidate
Title: Human Memory CD8 T Cells Polyfunctionality is Epigenetically Controlled by PRMT1
Date: Tuesday, January 17, 2017
Time: 2:00 pm
Place: MRB G03
Advisor: Dr. Jonathan Schneck

Pathobiology Thesis Seminar
Speaker: Yi-Hsin Lin
Ph.D. Candidate
Title: Generation of a spontaneous HPV-16 E6/E7 expressing pre-clinical tumor model for therapeutic intervention
Date: Monday, November 28, 2016
Time: 3:30 pm
Place: CRB II, 111
Advisor: Dr. TC Wu

Pathobiology Thesis Seminar
Speaker: Michael Ayars
Ph.D. Candidate
Title: RNA Expression Patterns in Pancreatic Intraepithelial Neoplasia
Date: Monday, October 31, 2016
Time: 3:00 pm
Place: CRB II, 111
Advisor: Dr. Michael Goggins

Pathobiology Thesis Seminar
Speaker: Alyssa Walker
Ph.D. Candidate
Title: Survival Pathways in Breast Cancer Cells during Glucose Deprivation
Date: Monday, August 1, 2016
Time: 1:00 pm
Place: CRB II, 1M 13
Advisor: Dr. Edward Gabrielson

Pathobiology Thesis Seminar
Speaker: AByunghak Kang, D.V.M.
Ph.D. Candidate
Title: Single-step BRAFV600E induction of right sided colon cancer phenotype by autonomous Wnt-activation and stem-cell expansion
Date: Monday, June 13, 2016
Time: 1:00 pm
Place: Owens Auditorium (CRB I & II Corridor)
Advisor: Dr. Steve Baylin
Co-Advisor: Dr. Hariharan Easwaran

Pathobiology Thesis Seminar
Speaker: Annie Hsieh
Ph.D. Candidate
Title: Oncogenic MYC Disrupts Molecular Clock and Metabolism in Cancer Cells and Drosophila
Date: Friday, March 18, 2016
Time: 1:00 pm
Place: Mountcastle Auditorium (PCTB)
Advisor: Dr. Chi Van Dang

Pathobiology Thesis Seminar
Speaker: Wan Yee Leong
Ph.D. Candidate
Title: Src Stimulates RUNX1 Trans-Activation to Favor Granulopoiesis
Date: Tuesday, February 23, 2016
Time: 2:00 pm
Place: Darner Conference Room, Turner G007
Advisor: Dr. Alan Friedman

Congratulations Jonathan Ling!

We are proud to announce the outstanding achievement of current Pathobiology graduate student, Jonathan Ling for his recently published article in Science, titled:
"TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD"
Science. 2015 Aug 7;349(6248):650-5.
doi: 10.1126/science.aab0983.
Article link:

Jonathan Ling comes from Boston, MA. He received his BS in Biomedical Engineering from Johns Hopkins in 2010. After taking several neuroscience classes, he joined a lab at Johns Hopkins and began researching the role of TARDBP and c9orf72 in the pathophysiology of FTD/ALS. Jon has taken advantage of the synergy between basic science and translational medicine that the Pathobiology program provides to further supplement his research experience.

Watch Jonathan Ling & Dr. Philip Wong take the ALS Ice Bucket Challenge! (As seen on CBS & Fox News)

Congratulations Dr. Cheryl Koh!

Congratulations to former Pathobiology graduate student, Cheryl Koh, Ph.D. for her recently published article in Nature, titled:
"MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis"
Nature 2015 Jul 11;523(7558):96-100. Epub 2015 May 11.

These authors contributed equally to this work.
Cheryl M. Koh & Marco Bezzi

Article Link:

Cheryl Mei-Yi Koh, Ph.D.
Agency for Science, Technology & Research
Institute of Molecular and Cell Biology (IMCB)
Singapore 138673, Singapore

I am currently studying the role of the protein arginine methyltransferases PRMT5 and PRMT7 in normal hematopoiesis and in Myc-induced lymphomas. My PhD research focused on the network of Myc-driven oncogenic processes in prostate carcinogenesis and was carried out in the lab of Angelo M De Marzo, MD, PhD, at the Johns Hopkins University School of Medicine, USA.

Congratulations on winning the Biotech & Healthcare Case Competition!

The Hopkins Graduate Student Consulting Club (JHGCC) successfully hosted a Biotech & Healthcare Case Competition on Friday, Apr 10, 2015 at the Homewood campus. The Case Competition was a great success with more than 50 teams (over 200 people) registered and 8 judges representing various sponsoring consulting firms on the day. The event culminated in 5 finalist team presentations in front of the client team from Johns Hopkins Medicine International, who were pleased to see the variety and depth of the recommendations that the teams came up with. This event provided undergraduates, graduate students, and postdocs interested in a career in consulting a hands-on opportunity to solve a complex business case and network with professionals in the field.

The 1st place winner is a three-person team from the Pathology Department

Biotech and Healthcare Case Competition Winners
To learn more about the The Hopkins Graduate Student Consulting Club (JHGCC) and the competition, please click here.

Pathobiology Graduate Program Student Awards

Scholar-in-Training Travel Award Winners

Heidi Hempel and Corey Porter were recipients of the Scholar-in-Training Travel Award to attend the AACR Sixth Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved. The conference took place November 9-12, 2014 at the Grant Hyatt San Antonio, Texas.

Allison Hanaford received the 2014 Women in Cancer Research Scholar Award for her abstract titled: Targeting glutamine metabolism as a therapeutic strategy in MYC-driven medulloblastoma.

Congratulations Heidi, Corey and Allison!