The Koliatsos Laboratory

Mouse brain rendered transparent with CLARITY to identify axonal abnormalities in long tracts after concussion. Abnormalities are shown as clusters of boutons (see for example left top).
Differentiated human stem cell grafts (red) synapse with rat motor neurons (green)

Research Interests

Founded in the late 1980s, our Lab has been exploring the fundamental mechanisms of neural responses to traumatic and degenerative signals as well as mechanisms of neural repair. Our current interests include: traumatic brain injury and models; mechanisms and treatments of traumatic axonopathies; molecular neuropathology of traumatic brain injury; and regeneration of circuits in the injured brain using stem cells and their products.