The Sol Goldman Pancreatic Cancer Research Center

What's New 2017


The Cancer Genome Atlas (TCGA) research network (the US government's effort to sequence the DNA in all of the major types of cancer), just published their results from a complete genetic analysis of 150 pancreatic cancers! In the August 14th issue of the journal CancerCell, the TCGA authors describe a detailed integrated (DNA, RNA and protein) analysis of the 150 pancreatic cancers. The major genes driving pancreatic cancer are described, and the authors identified two main subtypes of pancreatic cancer (basal-like/squamous and classical/progenitor). While this study does not have direct patient impact yet, it does represent a major milestone in our understanding of this disease. Special congratulations to the many scientists from Johns Hopkins who contributed to this study!

Cory Sandone and Carolyn Hruban created this medical illustration in honor of the study.

The Cancer Genome Atlas (TCGA) Research Network performed integrated genomic, transcriptomic and proteomic profiling of 150 pancreatic ductal adenocarcinomas (PDACs). PDACs (depicted as a star-shaped mass in the pancreas) are composed of a few neoplastic cells (marbles labeled with crabs) admixed with greater numbers of non-neoplastic cells (white marbles). The team employed a novel analytical strategy (depicted as the sieve) to identify neoplastic cell-specific molecular subgroups (depicted as the buckets of enriched populations of marbles with crabs).

Sol Goldman Professorship

Hruban, Goggins, & Rothman
A wonderful ceremony was held on Monday June 19th, establishing the Sol Goldman Professorship in Pancreatic Cancer Research in the Department of Pathology. This professorship honors the legacy of Sol Goldman and provides critical stability and flexibility to our faculty so that they can take advantage of important opportunities for innovative research. Michael Goggins, a world leader in the early detection of pancreatic cancer and long-term member of the Sol Goldman Pancreatic Cancer Research Center, was inducted as the first recipient of the Goldman Professorship. Congratulations Mike!

Pancreatic cancer patients may live longer by traveling to academic hospital for operation

A recent paper published in the Journal of the American College of Surgeons reports that traveling to an academic medical center such as Johns Hopkins for surgical resection of a pancreatic cancer is associated with higher quality surgical care. Although they found better care at high-volume surgical centers, they report that few patients travel for their cancer operations. To learn more, visit: or

Congratulations Dr. Weiss!

Dr. Matthew Weiss
Johns Hopkins pancreas surgeon Dr. Matthew Weiss was inducted into the Miller-Coulson Academy as a Miller-Coulson Scholar. This high honor recognizes clinical excellence- "The clinically excellent academic physician who has achieved a level of mastery in communication & interpersonal skills, professionalism & humanism, and negotiation of the healthcare system. Such physicians are exemplary with respect to diagnostic acumen, knowledge, and their scholarly approach to clinical practice. They exhibit a passion for patient care, and they explicitly model all of the above to medical trainees, earning them a reputation for being exceptional." Congratulations Dr. Weiss!