Johns Hopkins Pathology

  • Abdominal Pain
  • Dyspepsia
  • Nausea
  • Fever
  • Vomiting

Serous cystic neoplasms are twice as likely in women as men. Patient age ranges from 18-91years, with a median age of 70.
25-30% of patients are asymptomatic, however, most patients present with symptoms such as: abdominal or epigastric pain, dyspepsia, nausea, vomiting, fever , melena, or weight loss. Abdominal masses may be found upon physical examination.

In rare cases, patients develop complications from serous cysts. Symptoms from these complications include: left-sided portal hypertension due to splenic vein occlusion, obstructive jaundice, acute abdomen with hematoperitoneum due to rupture of the tumor, erosion vessels in and around the cyst, recurrent pancreatitis, ulceration of the duodenum causing GI hemorrhage, or Evan’s syndrome (autoimmune hemolytic anemia and immune thrombocytopenia).


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