The Sol Goldman Pancreatic Cancer Research Center

The National Familial Pancreas Tumor Registry

The History of the NFPTR

History of NFPTR chart

The National Familial Pancreas Tumor Registry (NFPTR) is a research registry that was established at The Johns Hopkins Hospital in 1994 by Dr. Ralph Hruban. He started the Registry so that scientists and doctors could learn more about pancreatic tumors. Over the past 14 years, the NFPTR has been a leader in the study of familial pancreatic cancer. There have been over 50 peer-reviewed publications that have stemmed from the NFPTR. These data have helped us:

  • Demonstrate that individuals with a family history of pancreatic cancer are at an increased risk of developing pancreatic tumors.
  • Understand the genetic basis (both inherited and non-inherited) of pancreatic cancer.
  • Demonstrate that genes are an important cause of pancreatic cancer.
  • Develop tools to identify individuals at high risk of pancreatic cancer.
  • Show that pancreatic tumors can be detected early in high-risk individuals. (For more information on our research, see the NFPTR newsletter links on the connect page.)

The NFPTR team includes clinicians and scientists from a variety of fields including epidemiology, pathology, gastroenterology, molecular biology, genetics, cytogenetics, surgery, radiology, radiation oncology and oncology. Having such a wide variety of clinicians and researchers who have dedicated their careers to learning more about pancreatic cancer truly enables the NFPTR to study pancreatic tumors from all angles. This multi-faceted approach has led to great advances in the field of pancreatic cancer research, and we still have a lot to learn. Click here to meet the team.