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Email emccarth@jhmi.edu
Phone (410) 614-3653

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Bone Histomorphometry Laboratory


Edward F. McCarthy, M.D.

Primary Appointment in Pathology; Secondary Appointment in Orthopedic Surgery


We have a bone biopsy histomorphology laboratory which is available for diagnostic problems and research. Our lab is able to process and cut undecalcified bone specimens. We are interested in metabolic bone disease and, in collaboration with other researchers, are studying the causes and response to treatment of metabolic bone diseases such as osteogenesis imperfecta and renal osteodystrophy. We are also interested in primary and secondary bone tumors. We are studying certain bone tumors, particularly cartilage tumors, with respect to rate of turnover as depicted in immunochemical techniques.

Publications
Khurana, J.S., McCarthy, E.F. Benign Cartilage Tumors. Diagnostic Histopathology. 20(5): 190-9, 2014.

Santiago-Dieppa, D.R., Hwang, L.S., Bydon, A., Gokaslan, Z.L., McCarthy, E.F. L4 and L5 Spondylectomy for En Bloc Resection of Giant cell Tumor and Review of the Literature. Evid based Spine Care J. 5:151-7, 2014.

Caturegli, P., McCarthy, E.F., Jackson, J.B., Hruban, R.H. The Pathology Residency Program of the Johns Hopkins University School of Medicine: A Model of Its Kind. Arch Pathol Lab Med. 139(3):400-6, 2015.

Mathios, D., Ruzevick, J., Jackson, C.M., Xu, H., Shah, S. Taube, J.M., Burger, P.C., McCarthy, E.F., Quinones-Hinojosa, A., Pardoll, D.M., Lim, M. PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment. J Neurooncol. 121(2):251-9, 2015.

Miller, P.D., McCarthy, E.F. Bisphosphonate-associated atypical sub-trochanteric femur fractures: Paired bone biopsy quantitative histomorphometry before and after teriparatide administration. Semin Arthritis Rheum. 44:477-82, 2015.



 


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