Susan H. Eshleman, M.D., Ph.D.
Primary Appointment in Pathology
Member, Graduate Program in Cellular and Molecular Medicine; Member, Graduate Program in Pathobiology
The HIV viruses in an infected individual are genetically diverse and evolve at a rapid rate in response to selective pressures. My laboratory studies HIV diversity and its impact on HIV infection and disease progression. Other areas of interest include analysis of HIV drug resistance, evaluation of interventions for HIV prevention, and the development of novel laboratory methods for HIV analysis.
Eshleman SH, Hudelson S, Redd AD, Wang L, Debes R, Chen YQ, Martens CA, Ricklefs SM, Selig EJ, Porcella SF, S Munshaw, SC Ray, Piwowar-Manning E, McCauley M, Hosseinipour MC, Kumwenda J, Hakim JG, Chariyalertsak S, de Bruyn G, Grinsztejn B, Kumarasamy N, Makhema J, Mayer KH, Pilotto J, Santos BR, Quinn TC, Cohen MS, and Hughes JP. Analysis of genetic linkage of HIV from couples enrolled in the HIV Prevention Trials Network 052 trial. J Infect Dis. 2011; 204:1918-1926.
Cousins MM, Konikoff J, Laeyendecker O, Celum C, Buchbinder SP, Seage GR, Kirk GC, Moore RD, Mehta SH, Margolick JB, Brown J, Mayer KH, Koblin BA, Wheeler D, Justman JE, Hodder SA, Quinn TC, Brookmeyer R, and Eshleman SH. HIV diversity as a biomarker for HIV incidence estimation: including a high resolution melting diversity assay in a multi-assay algorithm. J Clin Microbiol. 2014; 52:115-121.
Coates TJ, Kulich M, Zelaya CE, Celantano DD, Chariyalertsak S, Chingono A, Gray G, Mbwambo JKK, Morin FS, Richter L, Sweat M, van Rooven H, McGrath N, Fiamma A, Laeyendecker O, Piwowar-Manning E, Szerekes G, Donnell D, and Eshleman SH. Effect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes (NIMH Project Accept; HPTN 043): a cluster-randomised trial. Lancet Global Health. 2014. 2:e267-e277.