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Email sbagnas1@jhmi.edu
Phone (410) 502-0812

Serena M. Bagnasco, M.D.

Primary Appointment in Pathology


Research interests currently include pathologic aspects and molecular markers of renal allograft dysfunction, and of native kidney disease. Studies are ongoing exploring new sources of potential biomarkers that can improve distinguishing among different types of injury in the transplanted kidney. Digital pathology of morphologic features of native kidney biopsies is being applied in correlation with clinical and molecular parameters for the analysis of proteinuric glomerular diseases in large multicenter, prospective, observational studies.

Publications
Pisitkun T, Gandolfo MT, Knepper M, Bagnasco SM. Application of system biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Proteomics Clin. Appl. 2012;6(5-6):268-78.

Barisoni L, Nast CC, Jennette JC, Hodgin JB, Herzenberg AM, Lemley KV, Conway CM, Kopp JB, Kretzler M, Lienczewski C, Avila-Casado C, Bagnasco SM, Sethi S, Tomazewski J, Gasim AH, Hewitt SM. Digital pathology evaluation in the multicenter nephritic syndrome study network (NEPTUNE). Clin J Am Soc Nephrol. 2013;8:1449-59.

Bagnasco SM, Zachary AA, Racusen LC, Arend LJ, Carter-Monroe N, Alachkar N, Nazarian SM, Lonze BE, Montgomery RA, Kraus ES. Time Course of Pathologic Changes in Kidney Allografts of Positive Crossmatch HLA-Incompatible Transplant Recipients. Transplantation. 2014; 97:440-445.

Jackson AM, Sigdel TK, Delville M, Hsieh SC, Dai H, Bagnasco SM, Montgomery RA, Sarwal MM. Endothelial cell antibodies associated with novel targets and increased rejection. J Am Soc Nephrol. 2015; 26:1161-71.

Sampson MG, Robertson CC, Martini S, Mariani L, Lemley K, Gillies CE, Otto EA, Kopp JB, Randolph A, Vega-Warner V, Eichinger F, Nair V, Gipson DS, Cattran D, Johnstone D, O’Toole J, Bagnasco S, Song P, Barisoni L, Troost J, Kretzler M, Sedor J, and the Nephrotic Syndrome Study Network: Integrative genomics identifies novel associations with APOL1 risk genotype in African American NEPTUNE subjects. J Am Soc Nephrol 2015 (in press)

Bagnasco SM. Intimal arteritis in renal allografts: new takes on an old lesion. -Current Opinion in Transplantation, 2015 (in press).



 


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