Second opinions on adrenal cases are beneficial for pathologists:
- Diagnostic complexity arising from morphologic overlap and challenging differential diagnoses.
- Rarity of adrenal tumors, which limits exposure and experience among general pathologists.
- High clinical and therapeutic impact of accurate classification for patient management, prognosis, and genetic counseling.
A second opinion by an endocrine pathology specialist ensures diagnostic precision, guides optimal use of ancillary studies, and aligns the final diagnosis with the leading standards for adrenal cortical and medullary tumors.