Ordering Information

Epic Orderable Name:  FISH B-Cell ALL Panel

Epic Test Id:  LAB20362

Testing Includes:  See Mayo Clinic website for additional information.

     The Standard (diagnostic) B-ALL FISH panel includes testing for the following abnormalities, using the FISH probes listed:

• Hyperdiploidy, +4,+10,+17: D4Z1/D10Z1/D17Z1
• t(12;21)(p13;q22), ETV6/RUNX1 fusion, ETV6/RUNX1 D-FISH
• iAMP21, RUNX1 amplification, ETV6/RUNX1 D-FISH
• t(9;22)(q34;q11.2), BCR/ABL1 fusion, BCR/ABL1 D-FISH
• t(1;19)(q23;p13), PBX1/TCF3 fusion, PBX1/TCF3 D-FISH
• t(11q23;var), MLL (KMT2A) rearrangement, MLL (KMT2A) break-apart
• del(9p), CDKN2A deletions, CDKN2A/D9Z1
• t(14q32;var), IGH rearrangement, IGH break-apart
• del(17p), TP53 deletions, TP53/D17Z1
• 8q24.1 rearrangement, MYC break-apart
• t(Xp22.33;var) or t(Yp11.32;var), P2RY8 rearrangement, P2RY8 break-apart
• t(Xp22.33;var) or t(Yp11.32;var), CRLF2 rearrangement, CRLF2 break-apart

Aliases:  FISH B-CELL ALL Oncology Cancer Cytogenomics Cytogenetics

Testing Schedule:  Monday thru Friday

Turnaround Time:  7-14 Days

Order Priorities:  Routine

Performing Laboratory:  Mayo Clinic Labs

LOINC:  62369-4

Methodology:  Fluorescence Insitu Hybridization (FISH)

Ordering Restrictions:  Note: this test will be sent out to Mayo Clinic Laboratories.  The interpretive report will be placed in epic

Reference Lab Test Code:  BALLF

Specimen Requirements

Collection Container:  Green Top Tube - Sodium Heparin

Collection Volume:  2-3 mL

Minimum Volume:  1.0 mL

Specimen Stability:  Store room temperature (preferred), may be refrigerated. DO NOT FREEZE

Specimen Types:  Bone marrow

For Lab Staff

Performing Lab:  Mayo Clinic Labs

Performing Workstation:  JCCG JH Cancer Cytogenetics

LAB phone:  410-955-1258; specimens will be received M-F, between 8am and 4:30pm; Saturday's limited coverage; leave voice mail

Lab Notes

     - Test is performed by Mayo Clinic Laboratories. 
     - For send out, send to tube station 072 
     - Results in EPIC under Lab Results

     - Lab specimen shipping address, deliver to:
          Johns Hopkins Cytogenomics/Cytogenetics Lab
          600 N Wolfe Street
          Baltimore, MD 21287

     - Downtime - use Pathology 14 form