Barretts esophagus books 2

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Laura Wake, M.D.
Laura Wake, M.D.

Digital Step Forward : e-Learning Module for Hematopathology Education

Our study compared the effectiveness of an interactive e-learning module with a traditional text-based method for teaching peripheral blood smear analysis to pathology residents around the country. Participants completed a multiple-choice test on peripheral blood smear findings and then were randomized into completing an e-learning module or a PDF reading exercise with the same educational content. Respondents rated their experience and completed a post intervention test composed of the same ...

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Nicholas Roberts, Ph.D., Vet.M.B.
Nicholas Roberts, Ph.D., Vet.M.B.

Shedding New Light on ATM loss and Role in Pancreatic Cancer Risk

Pancreatic cancer is caused by the accumulation of multiple genetic changes that can either be inherited or acquired during a person’s lifetime. Inheriting a disease-causing variant in the ATM gene is associated with an increased risk of developing pancreatic cancer. However, as there are two copies of the ATM gene in every cell, a second genetic change must be acquired in ATM during a person’s lifetime to result in the development of pancreatic cancer. In this study, we used DNA sequencing a...

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John Gross, M.D., M.S.
John Gross, M.D., M.S.

Unique Features Spotlighted in Calcified Chondroid Mesenchymal Neoplasm

We studied the largest cohort (33 patients) of a rare and recently described soft tissue tumor known as “calcified chondroid mesenchymal neoplasm” (CCMN) which commonly harbor FN1-gene rearrangements. Our primary goals were to investigate the morphology, radiology, and clinical behavior in hopes to aid pathologist recognition and increase awareness as most cases were sent to The Johns Hopkins Hospital by other pathologists seeking expert pathology opinion out of concern for malignancy. Our re...

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Serena Bagnasco, M.D.
Serena Bagnasco, M.D.

Prognostic Value of Modified Oxford Score for Post-Transplant Recurrent IgA Nephropathy

This study examines the prognostic usefulness of the Oxford classification/MEST-C score (Mesangial and Endocapillary hypercellularity, Segmental sclerosis, Tubular atrophy-interstitial fibrosis, and the presence of Crescents) in biopsies of recurrent immunoglobulin A nephropathy (IgAN) in a North America multicenter study.

The results show that higher MEST-C scores are associated with higher risks of graft failure (adjusted hazard ratio 8.57 for score sums 2-3, and 61.32 for score sum...

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