Molecular Diagnostics staff

Molecular Diagnostics Lab

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Laboratory Tests & Services

Laboratory tests/services include:

  • Bone marrow engraftment assays
  • Next generation sequencing (NGS) panels for solid tumors and hematologic malignancies
  • Microsatellite instability testing
  • Quantitative BCR/ABL RT-PCR
  • Translocation assays for leukemias and soft tissue tumors
  • IGH and TCR rearrangement for B-cell and T-cell clonality
  • SNP array for 1p19q deletion and monosomy 6
  • Molar pregnancy genotyping
  • AR-V7 testing for advanced or castration-resistant prostate cancer
  • Telomere length measurement by flow cytometry and FISH

Contact

Hours of Operation: Monday-Friday: 8:30AM - 5:30PM (closed on weekends and holidays)
Phone: 410-955-8363
Email: molecularpathresults@jhmi.edu

Address:
Johns Hopkins Genomics - MDL
1812 Ashland Avenue
Room 245
Baltimore, MD 21205

Lab Staff

Directors Drs. Ming-Tseh Lin, James Eshleman, Christopher Gocke, and Rena Xian
Telomere Length Assay Dr. Mary Armanios
Manager Katie Beierl
Clinical Specialists (Assay Development) Lisa Haley and Emily Adams
Lead Technologists Kirstin Smith and Trisha James
Genetic Analysts Liqun Jiang and Suping Chen
Bioinformatics Aparna Pallavajjalla and Kevin He
Technologists Chrisley Pickens, Dilber Nurmemet, Jake Anderson, Jormoh Bellepu, Kiana Coche, Klarissa Juliano, Lauren Mulcahy, Marie Valerie Toure, Prisca Mbonu, Thomas Hebert, Ty Power, Victoria Alms, Victoria Gniazdowski

Shipping Instructions

The Molecular Diagnostics Laboratory is CAP and CLIA-certified and is licensed in Maryland, Pennsylvania, and Florida. The lab is not licensed to accept specimens from New York.

  • Please ship each specimen with a completed requisition form, including payment information.
  • For tissue specimens, include a copy of the surgical pathology report.
  • All specimens must be labeled with at least two patient identifiers (such as patient name, date of birth, or medical record number) which match the information on the accompanying documents.
  • See sample-specific shipping requirements below this page for - Blood and Bone Marrow, FFPE Tissue, and Buccal Swabs
  • Before shipping, please call the lab at 410-955-1438 or email molecularpathresults@jhmi.edu with any questions and to notify us of the shipment.

Shipping Address

Johns Hopkins Genomics - MDL
1812 Ashland Avenue
Room 245
Baltimore, MD 21205

Schedule

The lab is not able to accept deliveries on Saturdays or the following holidays (or observed holidays): New Year's Day, MLK Jr Day, Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day.

Specimen Requirements

Please see the Test Menu for specimen requirements for specific tests.

Blood and Bone Marrow

A. For AR-V7 testing, blood must be collected in yellow top ACD-A tubes. Specimens must be received within 24 hours of collection, or they will be rejected. See AR-V7 Requisition Form for detailed specimen requirements and shipping instructions.

  1. Obtain the appropriate Fedex shipping container before scheduling specimen collection.
  2. To ensure specimens are received within 24 hours of collection, collect specimens in the afternoon and ship overnight for first morning delivery.
  3. Please e-mail molecularpathresults@jhmi.edu with the Fedex tracking number.

B. For Telomere Flow FISH, keep specimens at room temperature, and ship overnight. Specimen requirements are:

  1. Adults: 12-18 cc in yellow top ACD tubes.
  2. Infants and children: Minimum 3 cc in lavender top EDTA tube.
  3. Samples will be rejected if blood tubes are not filled properly, if blood is received >72 hours of collection, or if blood was not stored at room temperature.

C. For all other tests, lavender top EDTA tubes are preferred. Refrigerate and ship overnight with cold pack. Do not freeze.

FFPE Tissue

  1. Include a copy of the surgical pathology report with the specimen.
  2. Blocks to be tested must contain tumor tissue. For Microsatellite Instability testing, normal tissue is also required. If no block containing Normal tissue is available, please submit blood or a buccal swab from the patient.
  3. FFPE tissue may be submitted as slides (preferred) or blocks.
  4. If slides are submitted:
    • Slides should be cut with PCR precautions.
    • H&E slides should be adjacent to unstained slides in series.
    • Please see the Test Menu for number of slides required for specific tests.
    • Package slides in appropriate containers to prevent breakage.
  5. These specimens may be shipped at ambient temperature.

Buccal Swabs

  1. Buccal swabs may be submitted for patient and/or donor for BMT Comprehensive testing and for Normal tissue for Microsatellite Instability testing.
  2. These specimens may be shipped at ambient temperature.