Tamara Lotan Farzana Faisal

Research & Faculty

Research

Pathobiology PhD student research is aimed toward the discovery of the basic mechanisms that cause disease with the goal of developing fresh insights leading to improved treatments or preventative measures.

Students are rigorously trained in mechanisms of disease by clinical and basic science experimental pathologists, have unparalleled access to human tissues and specimens in health and disease for translational research objectives and are required to complete translational rotations in which they are immersed in the practice of clinical pathology with direct relevance to their research projects. All facets of the program are geared towards this focus on human pathology, including innovative coursework on research reproducibility as relevant to human tissue-based methods.

Specializations

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Students are prepared with formalized classroom instruction in all areas of disease mechanisms. Under the guidance of faculty advisors, students undertake specialized training (including thesis research) in one of six programmatic areas:

  • Cellular & Molecular Pathology
  • Immunopathology
  • Microbiology & Infectious Disease
  • Neoplasia
  • Neuropathology
  • Vascular Biology & Hemostasis (Cardiovascular Disease)

Research Facilities

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Our students have access to the state of the art research facilities at Johns Hopkins for their experimental studies. 
 

Student researchers have access to core equipment and facilities as well as Department of Pathology facilities that include:

  • A research histology lab
  • A research immunohistochemistry lab
  • Molecular diagnostics and cytogenetics labs
  • A flow cytometry lab, computerized image analysis and transmission
  • Extensive tissue banks
  • A full-service photography lab
  • A departmental data system computer network

Our fully equipped laboratories support studies ranging from molecular, cellular, and physicochemical analyses through whole animal and informatics-based techniques.

Faculty & Their Research Interests

Our faculty have diverse research interests—ranging from cancer genetics to immunology to liver biology—but united by a common focus on human disease.

Richard F. Ambinder, M.D., Ph.D.

Richard F. Ambinder, M.D., Ph.D.

Professor, Oncology
Lymphoma; Kaposi's Sarcoma; Epstein-Barr Virus and Cancer; AIDS Associated Cancers; Lymphoma biology; Antitumor therapy; Antiviral therapy; Virology in human cancer
Faculty Profile

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Sarah R. Amend, Ph.D.

Assistant Professor, Urology and Oncology
Cancer metastasis; cancer therapy resistance; polyaneuploid cancer cells; evolutionary ecology
Faculty Profile

Robert Anders, M.D., Ph.D.

Robert A. Anders, M.D., Ph.D.

Associate Professor, Pathology - GI/Liver Pathology
Gastrointestinal and Liver Pathology; Liver cancer; Liver cell death and division
Faculty Profile

Renyuan Bai, M.B.B.S., Ph.D.

Renyuan Bai, M.B.B.S., Ph.D.

Associate Professor, Neurosurgery
Brain Cancer
Faculty Profile

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Ashwin Balagopal, M.D.

Associate Professor, Medicine, Division of Infectious Diseases
Virology; chronic viral infections; hepatitis B virus; hepatitis C virus; HIV-1; innate immunity
Research Lab | Faculty Profile

Stephen B. Baylin, M.D.

Stephen B. Baylin, M.D.

Virginia and D.K. Ludwig Professor for Cancer Research Professor of Oncology and Medicine
Epigenetics
Faculty Profile

William R. Bishai, M.D., Ph.D.

William R. Bishai, M.D., Ph.D.

Co-Director, Johns Hopkins Center for Tuberculosis Research; Professor of Medicine
Molecular biology of mycobacterium tuberculosis
Research Lab | Faculty Profile

Shyam Biswal, Ph.D., M.S.

Shyam Biswal, Ph.D., M.S.

Professor, Medicine and Oncology; Co-Director, Toxicology, Physiology and Molecular Mechanisms PhD Track
Environmental Health Sciences; Cigarette smoke; Lung diseases; Inflammation: Cancer; COPD; Emphysema; Asthma; Environmental stress response
Research Lab | Faculty Profile

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Challice Bonifant, M.D., Ph.D.

Assistant Professor, Pediatric Oncology
Immunotherapy; Cell engineering; Adoptive cell transfer; Cell therapy; Leukemia; Hematopoietic cell transplantation
Faculty Profile

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Gerald Brandacher, M.D., FAST

Professor, Vice Chair of Research and Director, Interdisciplinary Research and Innovation for the Surgical Sciences; Director, Vascularized Composite Allotransplantation (VCA) Laboratory, Department of Plastic and Reconstructive Surgery
Reconstructive transplantation; Donor-specific immune tolerance and immunomonitoring strategies
 

Fred Bunz, M.D., Ph.D.

Fred Bunz, M.D., Ph.D.

Director, Sidney Kimmel Comprehensive Cancer Center Cell Imaging Core Facility; Associate Professor, Radiation Oncology and Molecular Radiation Sciences
Loss of innate immunity during tumorigenesis; Human DNA damage responses and the cellular roles of p53
Faculty Profile

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Patrick Cahan, Ph.D.

Associate Professor, Institute for Cell Engineering, Dept. of Biomedical Engineering
Stem cell engineering; development and degenerative diseases of the synovial joint; computational biology
Cahan Lab | Faculty Profile

Patrizio Caturegli, M.D., M.P.H.

Patrizio Caturegli, M.D., M.P.H.

Director, Hypophysitis Center; Professor, Pathology - Immunopathology
Thyroid peroxidase (TPO); Thyroglobulin; Autoantibodies; Hurthle cell lesions; Congenital complete heart block; Sjogren's syndrome; Hypophysitis; Thyroiditis; Myocarditis; Endocrinology; Pituitary disease; Thyroid disease; Autoimmune disease
Autoimmune Diseases | Faculty Profile

Daniela Cihakova, M.D., Ph.D.

Daniela Ciháková, M.D., Ph.D.

Professor of Pathology, Clinical Immunology Laboratory
Myocarditis; APECED/Aire research
Research Lab | Faculty Profile

Isabelle Coppens, Ph.D.

Isabelle Coppens, Ph.D.

Professor, W. Harry Feinstone Dept. of Molecular Micro and Immunology, JHSPH
Toxoplasma; Plasmodium liver stage; Cryptosporidium; Host cell-parasite interactions; Parasitophorous vacuole; Nutrient uptake; Lipids; Cholesterol cell biology drug targeting
Faculty Profile

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Dao-Fu Dai, M.D., Ph.D.

Associate Professor (PAR), Cardiac Pathology
Mitochondrial and metabolic signaling in aging; Cardiac and Kidney diseases; Using mouse and hiPSC models of human diseases
Faculty Profile

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W. Brian Dalton, M.D., Ph.D.

Assistant Professor, Oncology, Division of Hematologic Malignancies
Biology and therapy of myeloid leukemias (MDS and AML); RNA splicing; Spliceosome mutations; Cancer metabolism; Abnormal hematopoietic differentiation
Research Lab
| Faculty Profile

Angelo De Marzo, M.D., Ph.D.

Angelo DeMarzo, M.D., Ph.D.

Associate Director of Cancer Research Pathology, SKCCC; Professor of Pathology, Oncology, and Urology
Tissue microarrays; Biomarker development; Biospecimen banking; MYC, PTEN and prostate cancer; Prostate cancer and inflammation
Research Lab | Faculty Profile

Xinzhong Dong, Ph.D.

Xinzhong Dong, Ph.D.

Professor, Neuroscience
Itch; Gentle touch; Hyperalgesia; Nerve injury; Neuropathic pain; MrgC agonism; Sensory circuits; Sensory neurons; Spinal ganglia; Sensory receptor cells; Neuronal imaging; Pain-sensing neurons; Genetic studies; Molecular studies; Somatosensation; Nociception; Pain; Heat
Faculty Profile

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Jonathan C. Dudley, M.D.

Assistant Professor, Oncology and Pathology
Solid tumor flow cytometry; Molecular genetic pathology; Cell-free RNA; Bladder cancer
Faculty Profile

Charles Eberhart, M.D., Ph.D.

Charles G. Eberhart, M.D., Ph.D.

Director, Neuropathology and Ophthalmic Pathology; Professor, Pathology
Tumor immunology; GU cancer; melanoma
Faculty Profile

James Eshleman, M.D., Ph.D.

James R. Eshleman, M.D., Ph.D.

Associate Director, Molecular Diagnostics Laboratory; Professor, Pathology - Gi/Liver
Molecular diagnosis of cancer; Genetic instability; Pancreatic cancer genetics and chemosensitivity
Faculty Profile

Susan Eshleman, M.D., Ph.D.

Susan H. Eshleman, M.D., Ph.D.

Director, HIV Prevention Trials Network (HPTN) Laboratory Center; Professor, Pathology - Transfusion Medicine
HIV diversity; HIV transmission, disease progression, and treatment outcomes; Evaluation of interventions for HIV prevention
Faculty Profile

Mohamed H. Farah, Ph.D.

Mohamed H. Farah, Ph.D.

Associate Professor, Departments of Neurology and Neuroscience
Genomics; Nerve regeneration; Nervous system
Faculty Profile

Alan D. Friedman, M.D.

Alan D. Friedman, M.D.

King Fahd Professor, Pediatric Oncology; Professor, Oncology
Regulation of Myeloid Differentiation and Transformation
Faculty Profile

Edward Gabrielson, M.D.

Edward W. Gabrielson, M.D.

Attending Pathologist, Johns Hopkins Hospital; Professor, Pathology - Molecular Pathology
Cancer biology; genomics
Faculty Profile

Kathleen Gabrielson, D.V.M., Ph.D.

Kathleen L. Gabrielson, D.V.M., Ph.D.

Associate Professor, Molecular and Comparative Pathobiology
Cardiovascular disease; Cancer; Pathology; Toxicology; Signal transduction; Cancer therapy
Faculty Profile

Luis Garza, M.D., Ph.D.

Luis Garza, M.D., Ph.D.

Professor, Departments of Dermatology and Cell Biology
Skin Regeneration; Skin Stem Cells; Wound Healing
Faculty Profile

Michael Goggins, M.B.B.Ch., M.D.

Michael Goggins, M.D.

Professor, Pathology - GI/Liver
Early detection of pancreatic cancer; Markers of pancreatic cancer; Pancreatic cancer screening; Familial pancreatic cancer; Pancreatic cancer epigenetics; Pancreatic cancer genetics
Research Lab
| Faculty Profile

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Michael Goldstein, M.D., Ph.D.

Assistant Professor, Department of Radiation Oncology and Molecular Radiation Sciences
DNA damage response; Epigenetics; Brain cancer; HPV-induced cancer screening
Research Lab
| Faculty Profile

Mary Kathryn Grabowski, Ph.D., Sc.M.

Mary Kathryn (Kate) Grabowksi, Ph.D.

Associate Professor, Pathology - Transfusion Medicine
Epidemiology and transmission dynamics of sexually transmitted viral infections (HIV, HPV, HSV); Sexual network structure and associations with viral STI transmission dynamics; Viral phylogenetics/phylodynamics
Faculty Profile

Abdel-Rahim Hamad, M.V.Sc., Ph.D.

Abdel Rahim A. Hamad, D.V.M., Ph.D.

Associate Professor, Pathology - Immunopathology
Type 1 diabetes; NKT cells; DN T cells; Obesity
Research Lab
| Faculty Profile

Gary S. Hayward, Ph.D.

Gary S. Hayward, Ph.D.

Professor, Oncology; Pharmacology and Molecular Sciences; Pathology
Virology; CMV; herpes viruses
Faculty Profile

Ho Won Jin

Won Jin Ho, M.D.

Assistant Professor, Cancer Immunology, GI Oncology
Cancer immunotherapy; Immunology; Cancer biology; Bioinformatics; and Medical oncology
Research Lab | Faculty Profile

Ahmet Höke, M.D., Ph.D.

Ahmet Höke, M.D., Ph.D.

Professor, Neurology and Neuroscience; Director, Neuromuscular Division
Developmental Neuroscience; Cellular and Molecular Neuroscience; Neurobiology of Disease
Faculty Profile

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Chuan-Hsiang Bear Huang, M.D., Ph.D.

Associate Professor, Pathology - GYN Pathology
RTK/Ras/PI3K/ERK signaling; cell migration; oncogenic signaling; cancer therapy
Faculty Profile

Robert Ivkov, M.Sc., Ph.D.

Robert Ivkov, M.Sc., Ph.D.

Professor, Radiation Oncology and Molecular Radiation Sciences
Development, characterization, and use of nanomaterials to target cancer; Selective heating with magnetic nanoparticles
Faculty Profile

Sanjay K. Jain, M.B.B.S., M.D.

Sanjay K. Jain, M.B.B.S., M.D.

Director, Center for Infection and Inflammation Imaging Research; Professor, Pediatrics
Tuberculosis; Pediatric tuberculosis; Imaging for infections and inflammatory diseases; CNS tuberculosis; Cellular and low-cost technologies to improve health care; Mycobacteria
Faculty Profile

Aaron James, M.D., Ph.D.

Aaron W. James, M.D., Ph.D.

Professor, Surgical Pathology; Co-director, Graduate Program in Pathobiology
Bone biology; Osteogenesis; Skeletal repair; Mesenchymal stem cells; Osteosarcoma
Research Lab
| Faculty Profile

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Hongpeng Jia, M.D., M.Sc.

Associate Professor, Division of Pediatric Surgery, Department of Surgery
Pulmonary Infectious and Inflammatory Diseases; Renin-Angiotensin System; Stem Cell Biology; innate immunity and developmental Immunology
Research Lab
| Faculty Profile

Richard J. Jones, M.D.

Richard J. Jones, M.D.

Professor, Oncology
Bone Marrow Transplantation; Cancer Stem Cells
Faculty Profile

Petros C. Karakousis, M.D.

Petros Karakousis, M.D.

Professor, Medicine, Infectious Diseases
Mycobacterium tuberculosis latency and persistence
Faculty Profile

David A. Kass, M.D.

David A. Kass, M.D.

Co-Director, Gastrointestinal Cancer Program; Professor, Oncology
Cardiomyopathy, Cardiovascular Disease, Cardiovascular Diseases, Geriatric Cardiology, Heart Disease, Heart Failure, Pacemakers
Research Lab
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Scott Kern

Scott E. Kern, M.D.

Professor, Oncology
Genetic Alterations in Pancreatic Cancer
Research Lab | Faculty Profile

Vassilis Koliatsos, M.D.

Vassilis E. Koliatsos, M.D.

Professor, Pathology; Neuropathology; Psychiatry and Behavioral Sciences
Brain blast injury; Traumatic and degenerative brain injury and repair; Alzheimers disease
Research Lab
| Faculty Profile

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Maximilian F. Konig, M.D.

Assistant Professor of Medicine, Division of Rheumatology, Department of Medicine, Ludwig Center for Cancer Genetics and Therapeutics; Institute for NanoBioTechnology
Autoimmunity; Precision immunotherapy; Chimeric antigen receptors; Chimeric T cell receptors; Cell engineering; Adoptive cell therapy; Bispecific antibodies
Research Lab
| Faculty Profile

Scott Krummey, M.D., Ph.D.

Scott M. Krummey, M.D., Ph.D.

Assistant Professor, Pathology-Transfusion Medicine
Transplant immunology; T cell biology; B cell biology; Antigen recognition; Histocompatibility; Coreceptor signaling pathways; Immunologic memory
Faculty Profile

Marikki Laiho, M.D., Ph.D.

Marikki Laiho, M.D., Ph.D.

Director, Division of Molecular Radiation Sciences; Professor, Radiation Oncology and Molecular Radiation Sciences
DNA damage biology; Regulation and targeting of RNA polymerase I transcription; Nucleolar stress response
Faculty Profile

Gyanu Lamichhane, Ph.D.

Gyanu Lamichhane, Ph.D.

Associate Professor, Medicine, Infectious Diseases
Biochemistry; Infectious disease; Mycobacterium tuberculosis: Genomics; Tuberculosis; RNA
Research Lab | Faculty Profile

H. Benjamin Larman, Ph.D.

Harry (Ben) Larman, Ph.D.

Associate Professor, Pathology - Immunopathology
'Next generation' DNA sequencing; Multiplex RNA quantification techniques
Research Lab
| Faculty Profile

John J. Laterra, M.D., Ph.D.

John J. Laterra, M.D., Ph.D.

Professor, Neurology
Brain malignancy, cancer stem cells, oncogenic signaling
Faculty Profile

Gabsang Lee, Ph.D.

Gabsang Lee, Ph.D.

Professor, Neurology and Neuroscience
Neural crest cell biology; Peripheral nerves disease; Congenital Insensitivity of Pain and Anhidrosis; Familial Dysautonomia; Charcot-Marie-Tooth 1A; Skeletal muscle; Duchenne muscular dystrophy; Facioscapulohumeral muscular dystrophy
Research Lab
| Faculty Profile

Tamara Lotan, M.D.

Tamara L. Lotan, M.D.

Professor, Pathology - Kidney/GU
Prostate cancer; Bladder cancer
Research Lab | Faculty Profile

Jun Luo, Ph.D.

Jun Luo, Ph.D.

Professor, Urology - James Buchanan Brady Urological Institute
Prostate cancer genomes; Prostate tumor biology; Prostate cancer
Faculty Profile

Leo Luznik, M.D.

Leo Luznik, M.D.

Professor, Oncology; Division of Hematologic Malignancies
Graft vs. Host Diseases; Leukemia; Non-Hodgkin's Lymphoma
Faculty Profile

Joseph L. Mankowski, D.V.M., Ph.D.

Joseph L. Mankowski, D.V.M., Ph.D.

Professor and Director, Molecular and Comparative Pathobiology
Neuropathology; Retrovirology
Faculty Profile

Nicholas J. Maragakis, M.D.

Nicholas J. Maragakis, M.D.

Director, ALS Center for Cell Therapy and Regeneration Research; Professor, Neurology
Amyotrophic Lateral Sclerosis (ALS), Lou Gehrig's Disease, Neurology
Faculty Profile

Lee J. Martin, Ph.D.

Lee J. Martin, Ph.D.

Director, Graduate Training Program in Pathobiology; Professor, Pathology and Neuroscience
Cell death; motor neuron diseases; Parkinson's disease
Faculty Profile

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Janielle P. Maynard, Ph.D.

Assistant Professor, Pathology and Oncology
Prostate cancer; pancreatic cancer; P2 purinergic receptors; cancer health disparities
Research Lab | Faculty Profile

Alan Meeker, M.A.T., Ph.D.

Alan K. Meeker, M.A.T., Ph.D.

Director, Oncology Tissue Services, Johns Hopkins Sidney Kimmel Comprehensive Care Center; Associate Professor, Pathology - Kidney/GU
Cancer; Quantitative fluorescence microscopy; Molecular pathology; Urology; Prostate cancer; Cancer biology; Telomeres; Pathology; Biology of aging; Cellular Senescence
Research Lab | Faculty Profile

Mollie K. Meffert, M.D., M.S., Ph.D.

Mollie K. Meffert, M.D., M.S., Ph.D.

Associate Professor, Biological Chemistry and Neuroscience
Systems, Cognitive and Computational Neuroscience; Cellular and Molecular Neuroscience; Neurobiology of Disease
Faculty Profile

Stephen J. Meltzer, M.D.

Stephen J. Meltzer, M.D.

Professor, Medicine - Gastroenterology; Oncology
Molecular pathophysiology and translational research in Barrett’s esophagus-associated neoplastic progression
Faculty Profile

Meaghan Morris, M.D., Ph.D.

Meaghan Morris, M.D., Ph.D.

Assistant Professor, Pathology; Neuropathology
Alzheimer's and related dementias; Aging; Tau
Research Lab
| Faculty Profile

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Heba Mostafa, M.B.B.Ch., Ph.D.

Director, Molecular Virology Laboratory; Associate Professor of Pathology
Developing molecular virology diagnostics; Viral genomic surveillance; Understanding the association between viral genomic evolution and outbreaks or severe disease
Research Lab
| Faculty Profile

Monica R. Mugnier, Ph.D.

Monica R. Mugnier, Ph.D.

Assistant Professor, Molecular Microbiology and Immunology
Antigenic variation; T. brucei; Kinetoplastid; Host-pathogen interactions; Bioinformatics; Genomics
Research Lab | Faculty Profile

Eric L. Nuermberger, M.D.

Eric Nuermberger, M.D.

Professor, Medicine - Infectious Diseases; International Health, Global Disease Epidemiology and Control, JHSPH
Tuberculosis drug development; Tuberculosis therapeutic vaccine development; Mycobacterium ulcerans disease (Buruli ulcer)
Faculty Profile

Drew M. Pardoll, M.D., Ph.D.

Drew M. Pardoll, M.D., Ph.D.

Director, Bloomberg Kimmel Institute for Cancer Immunotherapy; Professor, Oncology
Gene and cell therapy
Research Lab | Faculty Profile

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Suman Paul, MBBS, Ph.D.

Assistant Professor, Oncology
Antibody engineering; Antibody-drug conjugates; Bispecific antibodies; CAR T cell therapy; Lymphoma, Leukemia
Research Lab | Faculty Profile

Kenneth J. Pienta, M.D.

Kenneth J. Pienta, M.D.

Donald S. Coffey Professor, Urology; Director, Urology Research Laboratories; Director, Research, The James Buchanan Brady Urological Institute; Co-Director, Prostate Cancer Research Program, SKCCC; Professor, Oncology; Pharmacology and Molecular Sciences
Novel therapeutic development; Biomarker development; Metastasis; Tumor microenvironment; Ecology of cancer
Research Lab | Faculty Profile

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Jennifer L. Pluznick, Ph.D.

Associate Professor, Physiology, Johns Hopkins University School of Medicine
Renal physiology; GPCRs; gut microbiome; blood pressure; olfactory receptors
Faculty Profile

Martin G. Pomper, M.D., Ph.D.

Martin G. Pomper, M.D., Ph.D.

Director, Nuclear Medicine and Molecular Imaging; Director, Johns Hopkins Small Animal Imaging Resource; William R. Brody Professor of Radiology; Assoc. Director, JH In Vivo Cellular and Molecular Imaging Center; Co-Director, Cancer Molecular and Functional Imaging, SKCCC
Translational molecular imaging; small-molecule, peptide and antibody-based imaging and theranostic agents; PET, SPECT, optical and MR imaging; nanomedicine
Faculty Profile

Eric H. Raabe, M.D., Ph.D.

Eric H. Raabe, M.D., Ph.D.

Associate Professor, Oncology; Instructor, Pathology
Targeting stem cell factors and their downstream effectors in malignancy, specifically in brain tumors; Using human neural stem cells to create genetically accurate models of aggressive brain tumors; Disrupting the LIN28 pathway in brain tumors; Developing novel metabolic-based therapies to disrupt MYC-driven tumors
Faculty Profile

Giorgio Raimondi, M.Sc., Ph.D.

Giorgio Raimondi, M.Sc., Ph.D.

Associate Scientific Director, Transplant Immunology; Assistant Professor, Plastic and Reconstructive Surgery
T lymphocytes and regulatory T cell immunobiology
Faculty Profile

Linda M. Resar, M.D.

Linda M. Resar, M.D.

Professor, Medicine - Hematology; Oncology; Pathology
Basic research focus is hematologic malignancy and molecular mechanisms that lead to cancer.; Clinical research interests include sickle cell anemia
Faculty Profile

Gregory J. Riggins, M.D., Ph.D.

Gregory J. Riggins, M.D., Ph.D.

Irving J. Sherman Research Professor; Professor, Neurosurgery
Neuro-oncology; molecular targets; genomics
Research Lab | Faculty Profile

Nicholas Roberts, Ph.D., Vet.M.B.

Nicholas Roberts, Ph.D., Vet.M.B.

Assistant Professor, Pathology, Oncology
Pancreatic cancer
Faculty Profile

Richard Roden, Ph.D.

Richard B. S. Roden, Ph.D.

Co-Director, Cancer Prevention and Control Program, SKCCC; Professor, Pathology - GYN Pathology
Human papillomavirus (HPV); Ovarian cancer; HPV virology; HPV preventive vaccine; Ovarian cancer pathogenesis; Proteosome inhibitor; Experimental therapeutics
Faculty Profile

Kevan Salimian, M.D., Ph.D.

Kevan J. Salimian, M.D., Ph.D.

Assistant Professor, Pathology - Surgical Pathology
General Surgical Pathology; GI/Liver Pathology
Faculty Profile

Jonathan Schneck, M.D., Ph.D.

Jonathan P. Schneck, M.D., Ph.D.

Professor, Pathology - Immunopathology; Oncology - Immunology and Hematopoiesis
Immunology; T cell activation
Research Lab
| Faculty Profile

Cynthia L. Sears, M.D.

Cynthia L. Sears, M.D.

Professor, Medicine - Infectious Diseases; Oncology, Immunology and Hematopoiesis
Infectious diarrheal diseases; Cryptosporidiosis; Food borne disease; Bacteroides fragilis infections
Faculty Profile

Gregg L. Semenza, M.D., Ph.D.

Gregg L. Semenza, M.D., Ph.D.

Director, Vascular Program, Institute for Cell Engineering; Professor, Genetic Medicine
Protection of the heart against ischemia-reperfusion injury; Role of HIF-1 in cancer; Gene and stem cell therapy for ischemic cardiovascular disease; Molecular mechanisms of oxygen homeostasis; Genetic syndromes due to mutations in genes encoding transcription factors
Research Lab | Faculty Profile

Karen Sfanos, M.S., Ph.D.

Karen Sfanos, M.S., Ph.D.

Deputy Director of Education, Department of Pathology; Associate Professor, Pathology - Kidney/GU
Prostate cancer; molecular pathology; Infections and chronic inflammation; Microbiome
Research Lab | Faculty Profile

Dipali Sharma, M.S., Ph.D.

Dipali Sharma, Ph.D.

Professor, Oncology, Division of Women's Malignancies
Signaling Mechanisms; Bioactive Food Components; Novel Therapeutics; Tamoxifen Resistance; Metastasis; Adipocytokines; Obesity-Cancer Connection; Breast Cancer
Faculty Profile

Ie-Ming Shih, M.D., Ph.D.

Ie-Ming Shih, M.D., Ph.D.

Richard W. TeLinde Distinguished Professor, Department of Gynecology and Obstetrics; Professor, Gynecology and Obstetrics
Cancer pathogenesis; Cancer diagnostics; Molecular cancer therapy; Molecular and cellular biology
Research Lab| Faculty Profile

Robert Siliciano, M.D., Ph.D.

Robert F. Siliciano, M.D., Ph.D.

Investigator, Howard Hughes Medical Institute; Professor of Medicine and Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine
Treatment of HIV infection; HIV reservoirs; HIV cure strategies
Research Lab | Faculty Profile

Debasish Sinha, Ph.D.

Debasish Sinha, Ph.D.

Adjunct Associate Professor, Ophthalmology School of Medicine
Glial cell function; Autophagy and Phagocytosis in retinal pigmented epithelial cells
Research Lab

Verena Staedtke, M.D., Ph.D.

Verena Staedtke, M.D., Ph.D.

Director, Pediatric Neurofibromatosis, Johns Hopkins Comprehensive Neurofibromatosis Center; Associate Professor, Neurology
Mechanisms and development of novel therapeutics for the treatment of malignant brain tumors and neurofibromatosis
Faculty Profile

Charles Steenbergen, M.D., Ph.D.

Charles J. Steenbergen, M.D., Ph.D.

Professor, Pathology - Cardiovascular Pathology
Cardiovascular Diseases, particularly Ischemia-Reperfusion Injury
Faculty Profile

Saraswati Sukumar, Ph.D.

Saraswati Sukumar, Ph.D.

Professor, Oncology, Division of Women's Malignancies
Methylated genes as markers of breast cancer; Intraductal instillation for treatment of DCIS and prevention of breast cancer; HOX genes and their diverse oncogenic and tumor suppressor functions in breast cancer
Faculty Profile

Charlotte J. Sumner, M.D.

Charlotte J. Sumner, M.D.

Professor, Neurology & Neuroscience, Neuromuscular Medicine
Spinal muscular atrophy and Inherited Neuropathy
Faculty Profile

Shuying Sun, Ph.D.

Shuying Sun, Ph.D.

Associate Professor, Pathology; Physiology
ALS; RNA processing pathways; CRISPR technique-based therapeutic strategies
Research Lab
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Chloe L. Thio, M.D.

Professor, Medicine - Infectious Diseases
Hepatitis B virus virology; Immunology; Epidemiology; Hepatitis B virus cure; HIV-hepatitis B co-infection; HIV-hepatitis C co-infection; host genetics of viral hepatitis outcomes
Faculty Profile

Aaron Tobian, M.D., Ph.D.

Aaron A. Tobian, M.D., Ph.D.

Director, Pathology, Transfusion Medicine Division; Professor, Epidemiology
Transfusion transmitted infections; and HIV
Faculty Profile

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Eneda Toska, M.S., Ph.D.

Assistant Professor, Medicine-Oncology
Epigenetic regulation; mechanisms of resistance to targeted therapies; regulation of estrogen receptor activity in breast cancer
Research Lab
| Faculty Profile

Juan Troncoso, M.D.

Juan C. Troncoso, M.D.

Director, Clinical and Neuropathology Core; Professor, Pathology
Trauma of the brain and spinal cord; Forensic neuropathology; Neurodegenerative diseases, including Alzheimer's disease
Faculty Profile

Christopher B. Umbricht, M.D., Ph.D.

Christopher B. Umbricht, M.D., Ph.D.

Associate Professor, Surgery
Breast cancer; thyroid cancer; early cancer progression; genome-wide analyses; bioinformatics
Faculty Profile

Raphael P. Viscidi, M.D.

Raphael P. Viscidi, M.D.

Professor, Pediatrics, Stanley Division of Developmental Neurovirology; Oncology
Seroepidemiology of human coronaviruses; Population genetics of Neisseria gonorrhoeae; Development of avian influenza virus like particle (VLP) vaccine; Development of SARS-coronavirus vaccine; Pathogenesis and seroepidemiology of human polyomaviruses; Pathogenesis and seroepidemiology of human papillomavirus
Faculty Profile

Mei Wan, Ph.D.

Mei Wan, Ph.D.

Professor, Orthopaedic Surgery
Parathyroid hormone; LRP6; bone marrow mesenchymal stem/progenitor cells; Tissue repair/remodeling; Stem cell mobilization
Faculty Profile

Jiou Wang, M.D., Ph.D.

Jiou Wang, M.D., Ph.D.

Professor, Biochemistry and Molecular Biology, BSPH; Neuroscience, SOM
Cellular and molecular neuroscience; Neurobiology of disease
Faculty Profile

Tian-Li Wang, Ph.D.

Tian-Li Wang, Ph.D.

Director, Molecular Genetics Laboratory of Female Reproductive Cancer; Professor, Pathology
Cancer genetics; epigenomics; Chemoresistance in ovarian cancer; Early detection of cancer; Notch signaling; Female reproductive cancer; Chromatin remodeling and DNA damage repair
Research Lab | Faculty Profile

Philip Wong, Ph.D.

Philip C-Y Wong, Ph.D.

Professor, Pathology - Neuropathology; Neuroscience
Cellular and molecular neuroscience; Neurobiology of disease
Faculty Profile

Laura Wood, M.D., Ph.D.

Laura D. Wood, M.D., Ph.D.

Associate Professor, Pathology - GI/Liver; Oncology - GI Cancer
Cancer genomics; Pancreatic cancer; Premalignant precursor lesions
Research Lab | Faculty Profile

T-C Wu, M.D., M.P.H., Ph.D.

T-C Wu, M.D., M.P.H., Ph.D.

Director, Gynecologic Pathology Division; Professor, Pathology
CD8+ T lymphocytes; Cervical cancer; Vaccination; Human papillomavirus (HPV); HPV vaccine; Cellular pathology; Molecular pathology; T cell biology; Tumor immunology; HPV immunology
Research Lab | Faculty Profile

Yamada K photo

Kazuhiko Yamada, M.D., Ph.D.

Margery K. and Thomas Pozefsky Professor in Kidney Transplant Surgery, JHUSOM; Director of Xenotransplantation, JHH
Immune tolerance; Xenotransplantation; Kidney transplantation; Thymus transplantation; Hematopoietic transplantation
Faculty Profile

Yates Clayton photo

Clayton C. Yates, Ph.D.

John R. Lewis Professor of Pathology; Professor, Oncology and Urology, JHUSOM
Cancer health disparities and molecular pathology
Faculty Profile

Srinvasan (Vasan) Yegnasubramanian, M.D., Ph.D.

Srinvasan (Vasan) Yegnasubramanian, M.D., Ph.D.

Professor, Oncology; Pathology; Radiation Oncology and Molecular Radiation Sciences
Interplay of cancer epigenetics and genetics; Role of TOP2 in transcription and genomic instability; Androgen receptor signaling; Cancer biomarkers; Epigenetic modulators for cancer therapy
Faculty Profile

Jelani C. Zarif, M.S., Ph.D.

Jelani C. Zarif, M.S., Ph.D.

Assistant Professor, Oncology
Prostate Cancer Immunology
Faculty Profile

Hui Zhang, Ph.D.

Hui Zhang, M.S., Ph.D.

Director, Mass Spectrometry Core Facility, Center for Biomarker Discovery and Translation; Professor, Pathology - Clinical Chemistry
Proteomics, Protein modifications and functions; Proteome scale; Glycoproteins
Research Lab | Faculty Profile